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A Study to Evaluate 3 Dose Levels of Luvadaxistat of Adults With Negative Symptoms of Schizophrenia

Schizophrenia Clinical Trial

Official title:
A Phase 2, 12-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel Study to Evaluate Efficacy, Safety, Tolerability, and Pharmacokinetics of 3 Dose Levels of TAK-831 in Adjunctive Treatment of Adult Subjects With Negative Symptoms of Schizophrenia

Clinical Trial Summary

The purpose of this study is to determine whether add-on luvadaxistat is superior to placebo on the Positive and Negative Syndrome Scale Negative Symptom Factor Score (PANSS NSFS).

Clinical Trial Description

The drug being tested in this study is called luvadaxistat. Luvadaxistat is being tested to treat negative symptoms in participants who have schizophrenia. Participants will be randomly assigned (by chance, like flipping a coin) to one of the four treatment groups in the double-blind period-which will remain undisclosed to the participant and study doctor during the study (unless there is an urgent medical need): - Luvadaxistat 50 mg once daily - Luvadaxistat 125 mg once daily - Luvadaxistat 500 mg once daily - Placebo once daily ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03382639
Study type Interventional
Source Neurocrine Biosciences
Contact
Status Completed
Phase Phase 2
Start date January 4, 2018
Completion date January 12, 2021
View Details
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