Schizophrenia Clinical Trial
— CSrehacopSZOfficial title:
Implementation of REHACOP Cognitive Training Program in Schizophrenia
Verified date | June 2016 |
Source | University of Deusto |
Contact | n/a |
Is FDA regulated | No |
Health authority | Spain: Ethics Committee |
Study type | Interventional |
This study examined the efficacy of an integrative cognitive remediation program (REHACOP) to improve cognition, social cognition, clinical symptoms and functional outcome in patients with schizophrenia.
Status | Completed |
Enrollment | 111 |
Est. completion date | April 2014 |
Est. primary completion date | April 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 65 Years |
Eligibility |
Inclusion Criteria: - diagnostic criteria for Schizophrenia according to American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR) Exclusion Criteria: - evidence of alcohol or drug abuse in the last 30 days - previous history of significant lack of consciousness - mental retardation - relevant neurological or medical condition |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Spain | University of Deusto | Bilbao | Biskai |
Lead Sponsor | Collaborator |
---|---|
University of Deusto |
Spain,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in functional competence after receiving cognitive remediation | functional competence was measured with San Diego UCSD Performance-Based Skills Assessment- UPSA | 4 months | Yes |
Primary | Change in global functioning after receiving cognitive remediation | global functioning measured with Global Assessment of Functioning (GAF) | 4 months | Yes |
Primary | change in verbal memory after receiving cognitive remediation | Verbal memory performance was assessed with the Hopkins Verbal Learning Test-HVLT (Brandt and Benedict 2001) | 4 months | Yes |
Primary | change in processing speed after receiving cognitive remediation | Processing speed was assessed with Digit Symbol subtest from Wechsler Adult Intelligence Scale-III (Wechsler 1997) | 4 months | Yes |
Secondary | change in emotion perception after receiving cognitive remediation | emotion perception was assessed with Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT) | 4 months | Yes |
Secondary | change in clinical symptoms after receiving cognitive remediation | Clinical symptoms was measured with Positive and Negative Syndrome Scale (PANSS) | 4 months | Yes |
Secondary | change in social perception after receiving cognitive remediation | Social perception was assessed with the Social Featuring Recognition Test (SFRT) | 4 months | Yes |
Secondary | change in theory of mind after receiving cognitive remediation | Theory of mind was assessed with Happe Strange Stories Test | 4 months | Yes |
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