Schizophrenia Clinical Trial
Official title:
Comparison of Emotion-focused Cognitive Behavior Therapy for Patients With Schizophrenia With Standard Treatment: Effects on Psychological Parameters and Rehospitalisation
The present study is a pilot single-blind randomized controlled therapy study. Its aim is to assess the efficacy of an emotion-focussed form of Cognitive behavior Therapy that focusses on emotional processes that are involved in the formation and maintenance of delusions such as emotional stability, emotion regulation and self-esteem.
Cognitive Behavior Therapy for psychosis (CBTp) is an effective treatment for patients with
psychosis. Several meta-analyses showed an effect of CBTp in addition to antipsychotic
treatment of small to medium effect size with regard to positive symptoms, general
psychopathology and depression. Nevertheless, present research suggests that are especially
emotional processes are closely related to positive symptoms and delusions, such as negative
emotions, low self-esteem, depression and anxiety, whereas present interventions of CBTp
focus often especially on cognitive interventions in order to change delusions as well as
more cognitive risk factors for delusions such as reasoning biases and a dysfunctional causal
attribution style.
Thus, the aim of the present single-blind randomized-controlled pilot therapy study was to
assess the efficacy of a new form of emotion-focussed Cognitive behavior therapy for
psychosis with regard to change in positive symptoms and delusions in comparison to standard
treatment.
The main hypotheses are:
- Efficacy of CBT-E: patients with schizophrenia who receive CBT-E show a more pronounced
reduction of delusions (primary outcome), as well as a more pronounced reduction of positive
symptoms, depression and general psychopathology, a stronger improvement in general and
social functioning and will receive lower doses of antipsychotic medication (secondary
outcomes) at post-treatment.
;
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