Schizophrenia Clinical Trial
Official title:
Paliperidone Palmitate in Early Schizophrenia - A Retrospective, Non-interventional Study of Patients With Newly Diagnosed Schizophrenia Treated With Paliperidone Palmitate Over a 12-Month Period
The primary objective of this study is to explore hospitalization (number, length and reasons for psychiatric hospitalizations) in young, adult, newly diagnosed schizophrenia participants during the first 12 months of treatment with once monthly paliperidone palmitate in naturalistic clinical settings.
Status | Completed |
Enrollment | 90 |
Est. completion date | September 2015 |
Est. primary completion date | September 2015 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 29 Years |
Eligibility |
Inclusion Criteria: - Participant must be a man or woman aged at least 18 years but not more than 29 years at the time of the first injection of paliperidone palmitate - Participant must have a documented diagnosis of schizophrenia according to either Tenth Revision of the International Classification of Diseases and Related Health Problems (ICD 10) or Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM 4) - Participant's first psychotic episode suggestive of schizophrenia must have been clinically evident not longer than 1 year prior to the first injection of paliperidone palmitate - Participant must have documentation (medical records) of at least 12 months (365 +/- 31 days) continuous treatment with paliperidone palmitate administered for the first time as part of clinical practice. This documentation must have been completed in the participant's records before the initiation of the study site - Participant must have initiated paliperidone palmitate treatment after the launch date (ie, commercial availability) of paliperidone palmitate at his/her respective site Exclusion Criteria: - Participant has either an ICD 10 or DSM 4 axis I diagnosis other than schizophrenia - Participant was diagnosed with alcohol or drug dependence (except for nicotine and caffeine dependence) according to either ICD 10 or DSM 4 criteria within 1 month prior to initiation of paliperidone palmitate treatment or during the 12 month documentation period - Participant was treated with any long acting injectable antipsychotic prior to paliperidone palmitate initiation or with a long-acting injectable antipsychotic other than paliperidone palmitate during the 12 month documentation period - Participant received an investigational drug (including investigational vaccines) or used an invasive investigational medical device within 30 days prior to paliperidone palmitate initiation or during the 12 month documentation period - Participant participated in an interventional or a non-interventional clinical study during the 12 month documentation period |
Observational Model: Cohort, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Janssen Pharmaceutica N.V., Belgium |
Croatia, Russian Federation, Turkey,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of Hospitalizations | 12 months | No | |
Secondary | Number of Treatment Patterns of paliperidone palmitate as measured by patient records | 12 months | No | |
Secondary | Treatment response Based on clinical illness, symptom severity and measurements of functioning Score | 12 months | No | |
Secondary | Parameters of Psychosocial Functioning based on questionnaire | 12 months | No | |
Secondary | Medical Resource Utilization | 12 months | No | |
Secondary | Psychiatric hospitalizations preceding the first paliperidone palmitate injection | 12 months | No | |
Secondary | Number of Participants with Adverse Events | 12 months | Yes |
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