Schizophrenia Clinical Trial
Official title:
Mobile Health Technology to Enhance Abstinence in Smokers With Schizophrenia
This study is designed to evaluate if a treatment the investigators call iCOMMIT is effective at helping smokers with schizophrenia stop smoking. iCOMMIT is a smoking cessation treatment that combines mobile technology with behavioral strategies, counseling, and medications.
The purpose of this 2-arm randomized controlled trial (RCT) is to evaluate the efficacy of
Multi-Component Mobile-enhanced Treatment for Smoking Cessation (iCOMMIT) in helping
individuals with schizophrenia or other psychotic disorders stop smoking. Eligible
participants will be randomized to receive iCOMMIT, which includes smoking cessation
counseling, pharmacotherapy, and mobile technology components, or a control intervention that
includes smoking cessation counseling and pharmacotherapy, but no mobile technology
components. The control condition represents an intensive standard of care and helps control
for monitoring, counselor, time, and attention effects.
The primary outcome for the study will be self-reported and bio-verified prolonged smoking
abstinence at the 6-month follow-up. Self-reported prolonged abstinence will be verified by
saliva cotinine assay. Secondary outcomes will include 7- and 30-day point prevalence
abstinence at each assessment, where abstinence is defined as no tobacco use in the prior 7
or 30 days.
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