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Adjunctive Aripiprazole in the Treatment of Risperidone-Induced Hyperprolactinemia

Schizophrenia Clinical Trial

Official title:
Adjunctive Aripiprazole in the Treatment of Risperidone-Induced Hyperprolactinemia: A Randomized, Double-Blind, Placebo-Controlled, Dose-Response Study

Clinical Trial Summary

Hyperprolactinemia is a frequent consequence of treatment with typical antipsychotic agents and atypical antipsychotics such as risperidone. Recent studies have suggested that aripiprazole, a partial dopamine agonist, reduces the prolactin response to antipsychotics. Thus, we conducted this study to evaluate the dose effects of adjunctive treatment with aripiprazole on hyperprolactinemia in stable schizophrenic patients maintained with risperidone.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02013232
Study type Interventional
Source Beijing HuiLongGuan Hospital
Contact Jingxu Chen, master
Phone 86-13681394260
Email chenjx1110@163.com
Status Recruiting
Phase N/A
Start date February 2013
Completion date February 2014
View Details
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