Schizophrenia Clinical Trial
— MBPPOfficial title:
The Effectiveness of a Mindfulness-based Illness Management Program for Chinese Patients With Schizophrenia: An Randomised Controlled Trial
Verified date | July 2017 |
Source | The Hong Kong Polytechnic University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Only a few intervention studies have also focused on changing patients' negative thoughts and feelings towards the illness and their relationship to the suffering caused by those thoughts, which is evidenced to empower psychosocial functioning and control of distressing thoughts in severe depression and psychotic disorders by using the Mindfulness-Based Stress Reduction program. This controlled trial is designed to test the effects of a mindfulness-based Illness management program (MBPP) for Chinese patients with schizophrenia on their symptom severity, illness insight and psychosocial functioning.
Status | Completed |
Enrollment | 449 |
Est. completion date | April 2017 |
Est. primary completion date | June 2016 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 64 Years |
Eligibility |
Inclusion Criteria: - outpatients; - aged 18+; and - diagnosed as schizophrenia and other psychotic disorders (< or =5 years) according to the Diagnostic and Statistical Manual, 4th edition, as ascertained by the Structured Clinical Interview (SCID-I). Exclusion Criteria: - not able to understand the psycho-education content and Chinese; - mentally unstable at recruitment; and - with co-morbidity of other severe mental health problems such as depression and substance misuse. |
Country | Name | City | State |
---|---|---|---|
China | Jilin Medical College | Jilin | Jilin |
Hong Kong | KH/LKS Specialty OPD | Shatin | NT |
Hong Kong | TM Psy Centre | Tuen Mun | NT |
Taiwan | Taipei Medical University | Taipei | Xinyi |
Lead Sponsor | Collaborator |
---|---|
The Hong Kong Polytechnic University | Hospital Authority, Hong Kong, Jilin Medical College, China, Taipei Medical University, Taiwan |
China, Hong Kong, Taiwan,
Chien WT, Bressington D, Yip A, Karatzias T. An international multi-site, randomized controlled trial of a mindfulness-based psychoeducation group programme for people with schizophrenia. Psychol Med. 2017 Sep;47(12):2081-2096. doi: 10.1017/S0033291717000 — View Citation
Chien WT, Lee IY. The mindfulness-based psychoeducation program for Chinese patients with schizophrenia. Psychiatr Serv. 2013 Apr 1;64(4):376-9. doi: 10.1176/appi.ps.002092012. — View Citation
Chien WT, Thompson DR. Effects of a mindfulness-based psychoeducation programme for Chinese patients with schizophrenia: 2-year follow-up. Br J Psychiatry. 2014 Jul;205(1):52-9. doi: 10.1192/bjp.bp.113.134635. Epub 2014 May 8. — View Citation
Lam, A.H.Y., & Chien, W.T. (2016). The effectiveness of mindfulness-based intervention for people with schizophrenia: A systematic review. Neuropsychiatry (London), 6(5), 208-222.
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Specific Level of Functioning Scale | Patients' levels of psychosocial functioning will be assessed with the Specific Level of Functioning Scale at baseline and one week, 6 months, 12 months and 24 months follow-up. | from recruitment to 24-month follow-up | |
Other | Six-item Social Support Questionnaire | Patients' perceived social support will be assessed with the Six-item Social Support Questionnaire at baseline and one week, 6 months, 12 months and 24 months follow-up. | from recruitment to 24-month follow-up | |
Primary | Rehospitalization rates | Average amount (number) and length of hospital stay of the patients over previous six months will be assessed at recruitment and one week, 6 months, 12 months and 24 months after the interventions completed. | from recruitment to 24-month follow-up | |
Primary | Positive and Negative Syndrome Scale | The Positive and Negative Syndrome Scale assesses the severity of psychotic symptoms on three subscales: positive symptoms (7 items), negative symptoms (7 items) and general psychopathology (16 items). will be assessed at recruitment and one week, 6 months, 12 months and 24 months after the interventions completed. Symptom remission rate over the follow-up periods are also assessed. Complete remission was defined as 4-month simultaneous ratings of all individual items in PANSS as score =3. | from recruitment to 24-month follow-up | |
Secondary | insights to illness and treatment | Patients' insight and attitudes to illness and treatment will be measured with the Insight and Treatment Attitudes Questionnaire at recruitment and one week, 6 months, 12 months and 24 months after the interventions completed. | from recruitment to 24-month follow-up |
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