Cognitive Training for Patients With Schizophrenia

Schizophrenia Clinical Trial

Official title:

Cognitive Training for Patients With Schizophrenia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01521026
• Other study ID #: NARSAD Young Investigator
• Status: Completed
• Phase: N/A
• Start date: September 2003
• Est. completion date: August 2009

Study information

• Verified date: June 2023
• Source: University of California, San Diego
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This research on cognitive training addresses the following questions: 1. Does cognitive training lead to improved cognition, functional abilities, psychiatric symptoms, treatment adherence, or quality of life in patients with psychoses? 2. What are the neurocognitive and non-cognitive factors that predict good outcomes following cognitive rehabilitation? In addition to verbal learning and memory, immediate verbal memory, vigilance, and executive functioning, the cognitive training intervention attempted to improve prospective memory ability (i.e., the ability to remember to do things in the future, such as take medications or attend a doctor's appointment).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 69
• Est. completion date: August 2009
• Est. primary completion date: August 2009
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Primary psychotic disorder (including schizophrenia, schizoaffective disorder, psychotic mood disorder, or psychosis NOS)
• Age 18 or older
• Fluency in English

Exclusion Criteria:

• Dementia
• Neurological conditions affecting cognition
• Mental retardation
• Substance use disorder within the past month
• Participation in other intervention trials

Related Conditions & MeSH terms

• Other Primary Psychotic Disorders
• Psychotic Disorders
• Schizoaffective Disorder
• Schizophrenia

Intervention

Behavioral:
• Cognitive Training
12-week compensatory cognitive training in group format

Locations

Country	Name	City	State
United States	UCSD Outpatient Psychiatric Services	San Diego	California

Sponsors (2)

Lead Sponsor	Collaborator
University of California, San Diego	National Alliance for Research on Schizophrenia and Depression

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	UCSD Performance-based Skills Assessment Total Score (Measures Functional Capacity)	Performance-based measure of functional capacity in five domains: Communication, Finance, Recreation Planning, Transportation, and Household Chores Scale ranges from 0-100. Subscales are summed to yield the total score. Higher scores represent better performance.	3 months
Secondary	Hopkins Verbal Learning Test Percent Retained	Verbal list learning task with three learning trials and a delay trial. Percent retained refers to the percentage of items recalled at the delay trial, compared to the third learning trial.; Score ranges from 0-100. Higher scores represent better performance.	3 months