Prevalence of Dissociative Disorders in Children

Schizophrenia Clinical Trial

Official title:

Prevalence of Dissociative Disorders in Children in a Population Supported in the Medico-social and Health Structures in Provence Alpes Cote d'Azur

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01512641
• Other study ID #: 11-API-01
• Status: Completed
• Phase: N/A
• First received: December 13, 2011
• Last updated: January 31, 2014
• Start date: December 2011
• Est. completion date: May 2013

Study information

• Verified date: January 2014
• Source: Centre Hospitalier Universitaire de Nice
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Committee for the Protection of PersonnesFrance: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
• Study type: Interventional

Clinical Trial Summary

Schizophrenia beginning before 18 years is a clinical entity not well known because of its low incidence and difficulties in the clinical diagnosis.

However, in the investigators clinical practice, due to the specialization of the investigators service, the investigators are led to hospital to receive important feel active of patients meeting the Diagnostic and Statistical Manual of Mental Disorders IV text revision (DSM IV-TR) precose schizophrenia.

The work of us team on the theme of the relationship between Pervasive Developmental Disorders and precose Schizophrenia led us to hypothesize that a number of children in care in the medical and educational institutes, hospitals and day shelters therapeutic part-time symptoms of schizophrenia or a line real early diagnosis of schizophrenia undervalued or not diagnosed.

The main goal is to estimate the prevalence of dissociative disorders in a population of children in care institutions and medical education in child psychiatry in hospitals and others structures.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 301
• Est. completion date: May 2013
• Est. primary completion date: May 2013
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 7 Years to 18 Years

Eligibility

Inclusion Criteria:

• 7 to 18 years

• Supported in the partner institutions of the study

• IQ>35 on the certificate of orientation of the Maison Départementale des Personnes Handicapées (MDPH)

• Obtaining the agreement of parents and children

Exclusion Criteria:

• QI<35 on the certificate file Guidance MDPH

• Children not speaking french

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Conversion Disorder
• Dissociative Disorders
• Schizophrenia

Intervention

Other:
• Primary stage
Kiddie-Schedule for Affective Disorders and Schizophrenia
• Secondary stage
children who are positive to the kiddie-SADS (primary stage), will take the tests: PANSS, Scale for the Assessment of Negative Symptoms (SANS), ADI-R, scale TLC and WISC IV

Locations

Country	Name	City	State
France	Psychiatrie infanto-juvénile - Centre Hospitalier d'Antibes	Antibes
France	Psychiatrie infanto-juvénile-Pôle femme-mère -enfant	Fréjus
France	Service de psychiatrie de l'enfant et de l'adolescent	Marseille
France	Service de psychiatrie de l'enfant et de l'adolescent	Nice

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire de Nice

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Rate of children diagnosed with dissociative disorders	Rate of children diagnosed with dissociative disorders: children positive for the test Kiddie-Schedule for Affective Disorders and Schizophrenia (Kiddie-SADS).	between 2 and 4 hours depending children	No
Secondary	Percentage of children positive for test: Autism Diagnostic Interview-Revise (ADI-R).		1 day on average	No
Secondary	Scores of three dimensions of schizophrenia in the Positive And Negative Syndrome Scale (PANSS)	3 dimensions: positive symptoms, negative symptoms and general psychopathology, based on these scores the diagnostic subtype of schizophrenia is established.	4 hours	No
Secondary	Score at the Test Lillois de Communication (TLC)		30 minutes	No
Secondary	Score on the Wechsler Intelligence Scale for Children-Fourth Edition (WISC IV)subtests and overall intelligence quotient (IQ).		4 hours	No
Secondary	Response time to test verbal fluency, scores on the Trail Making Test A (TMT) and TMT B.		30 minutes	No