Bone Density in Patients With Schizophrenia

Schizophrenia Clinical Trial

Official title:

Bone Mineral Density in the Korean Patients With Chronic Schizophrenia With Alcohol Abuse

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00540267
• Other study ID #: BMD07
• Secondary ID: Korea Health 21
• Status: Completed
• Phase: N/A
• First received: October 4, 2007
• Last updated: November 3, 2008
• Start date: November 2007
• Est. completion date: November 2008

Study information

• Verified date: October 2008
• Source: Inje University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Korea: Food and Drug Administration
• Study type: Observational

Clinical Trial Summary

People with chronic mental disorder such as schizophrenia and alcohol abuse are high risk groups for developing osteoporosis.

To evaluate the prevalence of bone mineral density in men patients with schizophrenia with alcohol abuse, the investigators will compare bone mineral density between patient with schizophrenia with and without alcohol abuse.

Description:

People with schizophrenia has been known as a high risk groups for developing osteoporosis, because of lack of exercise, poor nutrition and high rate of smoking. Those with alcohol abuse may be higher risk group than one with schizophrenia without alcohol abuse, because they frequently have several medical problems such as liver dysfunction, Vitamin D deficiency, hyperparathyroidism and those medical condition increase risk for developing osteoporosis. Also alcohol itself can increase bone loss too by disturbing bone remodeling and enhancing bone fragility. To compare the prevalence of bone mineral density in patients with schizophrenia with alcohol abuse to those without alcohol problem, we will investigate BMD in large population of Korean patients with those illnesses.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 300
• Est. completion date: November 2008
• Est. primary completion date: November 2008
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 80 Years

Eligibility

Inclusion Criteria:

• DSM-IV diagnosis of schizophrenia

• Onset of illness more than 5 years.

Exclusion Criteria:

• No severe Medical and endocrinological disorder

Study Design

Observational Model: Case Control

Related Conditions & MeSH terms

• Alcohol Abuse
• Alcoholism
• Schizophrenia

Intervention

Other:
• No Intervention
No Intervention

Locations

Country	Name	City	State
Korea, Republic of	Joo-Cheol Shim	Busan

Sponsors (1)

Lead Sponsor	Collaborator
Inje University

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The change of bone mineral density		cross sectional and prospective	Yes
Secondary	The effects of Smoking and antipsychotic drug on BMD		Cross sectional Study	Yes