Schizophrenia Clinical Trial
Official title:
Naturalistic Multicenter Study of Changes in Auditory Verbal Hallucination During Atypical Antipsychotic Treatment of Schizophrenia
The purpose of this study is to evaluate the changes in various aspects of auditory verbal hallucinations during 24-week antipsychotic treatment in naturalistic condition.
Auditory verbal hallucinations (AVH), meaning the experience of hearing voices, occur in
60-75% of patients with schizophrenia. Patients experiencing persistent AVH tend to be
interrupted in their daily routines and have trouble keeping regular jobs due to the
intrusiveness or abusive contents of voices. In addition, auditory hallucinations are
reported to remain even after disappearance of other psychotic symptoms in many patients
with schizophrenia spectrum disorders after treatment with typical antipsychotics.
The study involves detailed phenomenological assessments of AVH and other psychotic
symptoms, as well as side effects of atypical antipsychotics.
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Observational Model: Case Control, Time Perspective: Prospective
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