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NCT00071604 Clinical Trial

Medication Adherence in Older People With Psychosis

Schizophrenia Clinical Trial

Official title:
Medication Adherence in Older Psychotic People

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00071604
Other study ID # R01MH062849
Secondary ID R01MH062849DATR
Status Active, not recruiting
Phase N/A
First received October 29, 2003
Last updated May 3, 2013
Start date September 2002
Est. completion date May 2007

Study information
Verified date April 2008
Source Veterans Medical Research Foundation
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Interventional

Clinical Trial Summary

This study will determine whether Medication Adherence Therapy (MAT) can improve medication adherence and lower the risk of rehospitalization in older patients with psychosis.

Description:

Psychoses are among the most common and serious psychiatric disorders. Currently, the most effective treatment for psychoses involves the use of antipsychotic or neuroleptic medications. Unfortunately, pharmacologic regimens often do not achieve their goals because of poor medication adherence. Nonadherence to antipsychotic treatment is a considerable public health problem that leads to myriad clinical and economic burdens, including psychotic relapse, increased clinic and emergency room visits, and rehospitalization.

Participants in this study are randomly assigned to receive either MAT or supportive treatment for 12 weeks. MAT is given in 15 sessions and consists of motivational interviewing, education, and social skills and behavior modification. Individual MAT sessions are held in Weeks 1 and 12; small group sessions take place in Weeks 2 through 11. Three monthly booster group sessions begin in Week 16. Participants are assessed at baseline and at 3, 6, and 12 months. Medication adherence, psychopathology, quality of life, medication side effects, health beliefs, and functioning are assessed.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 240
Est. completion date May 2007
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 40 Years and older
Eligibility Inclusion Criteria:

- DSM-IV criteria for schizophrenia or schizoaffective disorder

- Outpatient status at the time of enrollment

- Currently prescribed maintenance treatment with antipsychotic medication (typical or atypical, oral or depot)

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind

Related Conditions & MeSH terms

Intervention

Behavioral:
• Medication Adherence Therapy

• Friendly Support Group

Locations
Country Name City State
United States Division of Geriatric Psychiatry Center (University of California, San Diego) San Diego California

Sponsors (2)
Lead Sponsor Collaborator
Veterans Medical Research Foundation National Institute of Mental Health (NIMH)

Country where clinical trial is conducted

United States, 

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