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Scar clinical trials

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NCT ID: NCT01459666 Terminated - Scar Clinical Trials

Forehead Scars Following Mohs Micrographic Surgery and Reconstruction for Skin Cancer

Start date: September 2011
Phase: Phase 4
Study type: Interventional

This study will test if the use of DysportTM (abobotulinumtoxinA) improves wound healing and scarring after Mohs surgery. Research in the laboratory as well as previous studies in humans have shown improved wound healing and scarring with the use of a similar medication called Botox. Dysport may improve wound healing and scarring by relaxing facial muscles and therefore minimizes the muscle tension and possibly the inflammation around the wound.

NCT ID: NCT01433198 Withdrawn - Burns Clinical Trials

Aquatic Training in Patients With Severe Scarring

Start date: May 2018
Phase: N/A
Study type: Interventional

Aim: - to investigate the effects of an aquatic exercise program in patients with severe scars Patient population: - 10 patients of at least 18 years old - patients with scars after burns or other severe skin injuries - stratification into two groups: an intervention group and a control group Method: - 8 patients will participate in the aquatic exercise group and 2 patients in the control group - assessment of physical fitness parameters, scar tissue and psychosocial impact Hypothesis: - patients of the aquatic exercise group will recover sooner and better (physically and psychologically) than patients of the control group

NCT ID: NCT01429402 Recruiting - Scar Clinical Trials

Botulinum Toxin to Improve Results in Cleft Lip Repair

Start date: July 2000
Phase: Phase 3
Study type: Interventional

Botulinum toxin type A (Botox; Allergan, Inc., Irvine, Calif) is widely used for facial rejuvenation and many other medical indications. It induces chemodenervation through its action on the presynaptic neuron, preventing release of acetylcholine, which leads to functional denervation of striated muscle for 2 to 6 months after injection. The use of botulinum toxin injection to reduce the facial scar is logical because this could reduce the tensile distracting force of the upper lip caused by the orbicularis oris muscle pull. Tollefson has demonstrate that botulinum toxin injection has decrease lip tension after primary lip repair in 3 children at 3-6 months of age The main aim of this randomized trial is to compare whether post-operative peri-surgical-injection of botulinum toxin into bilateral orbicularis oris muscles can improve scar formation for both primary and secondary cleft lip surgery.

NCT ID: NCT01409863 Withdrawn - Scar Clinical Trials

Fractional Laser Therapy and Dermabrasion for Scar Revision

Start date: March 2010
Phase: N/A
Study type: Interventional

The goals of this study will be to compare the safety and efficacy of fractional photothermolysis (Fraxel) with dermabrasion when used for scar revision.

NCT ID: NCT01177358 Recruiting - Scar Clinical Trials

Botox in the Healing of Surgical Wounds of the Neck

Start date: September 2011
Phase: Phase 2
Study type: Interventional

The investigators hypothesize that Botox A will reduce scarring and improve healing of surgical neck wounds.

NCT ID: NCT01005992 Not yet recruiting - Scar Clinical Trials

Fractional Photothermolysis for the Treatment of Burn Scars

Start date: November 2009
Phase: Phase 1
Study type: Interventional

The aim of our study is to determine the effect of fractional photothermolysis laser in the treatment of burn scars.

NCT ID: NCT00970671 Completed - Scar Clinical Trials

Treatment of Surgical Scars Using the Pulsed Dye Laser

Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether treatment of fresh surgical scars with a pulsed dye laser using purpura-inducing settings will improve clinical appearance better than one using non-purpura-inducing settings or no treatment.

NCT ID: NCT00700791 Terminated - Scar Clinical Trials

Efficacy of Natural Vitamin E Tocotrienol on the Treatment of Surgical Scars

Start date: July 2008
Phase: Early Phase 1
Study type: Interventional

The overall goal of this study is to determine the efficacy of tocotrienol (TCT), a natural form of vitamin E, in preventing or reducing scar formation in human skin wounds as well as the basal levels of TCT in normal human skin and adipose tissue.

NCT ID: NCT00585286 Completed - Acne Clinical Trials

Fractional Resurfacing Device for Treatment of Acne Scarring

Start date: March 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this research study is to evaluate the safety and effectiveness of a new investigational laser device for treatment of acne scarring, for improvement in the appearance of surface texture and topography (recessed or uneven surfaces).

NCT ID: NCT00506363 Terminated - Scar Clinical Trials

Safety and Efficacy of Different Onset Times of Treatment With Pulsed Dye Laser on Improvement of Surgical Scars

Start date: January 2008
Phase: N/A
Study type: Interventional

The appearance of skin after surgery plays an important role in patient's self confidence and life style. In fact, Keloids and hypertrophic scars are abnormal wound responses appearing in predisposed individuals after surgery. Among different kind of lasers, used to improve the appearance of hypertrophic scars and keloids, pulsed dye laser is now being used successfully in treatment of scars. Pulsed dye laser is effective in improving the color, height, texture, and elasticity of scars. Also, treatment with this technique is noninvasive, minimally uncomfortable, and requires no anesthesia. This study will assess the efficacy and safety of different onset times of treatment with pulsed dye laser on improvement of surgical scars.