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Scar clinical trials

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NCT ID: NCT06437912 Completed - Scar Clinical Trials

Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"

Start date: March 23, 2023
Phase: Early Phase 1
Study type: Interventional

Each year, millions of burn, trauma, or surgical patients worldwide suffer from scarring that severely affects their quality of life and social functioning. In order to prevent and treat diseases related to abnormal scar hyperplasia, clinicians and researchers have adopted various methods, such as scar grinding, surgical resection, drug injection in scar tissue, cryotherapy, laser and so on. However, these methods can not effectively inhibit the abnormal proliferation of scars and improve the adverse effects of existing scars on patients. To date, there is no accepted gold standard for the effective treatment and improvement of abnormal scar tissue.

NCT ID: NCT06386549 Recruiting - Burns Clinical Trials

Effect of a Tele-rehabilitation Programme in Children With Burns: a Randomized Controlled Trial

Start date: November 14, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare tele-rehabilitation and routine post-discharge rehabilitation in children with burn injuries. The main questions it aims to answer are: - Is tele-rehabilitation better for improving the quality and outcomes of care for burn children? - Is tele-rehabilitation more effective in improving scar management in children with burns injuries? - Is tele-rehabilitation more effective in improving perceived stress in parents of children with burns injuries?

NCT ID: NCT06349733 Active, not recruiting - Scar Clinical Trials

Effectiveness of Botulinum Toxin A in Preventing Scar Formation and Initial Exploration of "Optimal Concentration"

Start date: March 23, 2023
Phase: Early Phase 1
Study type: Interventional

Each year, millions of burn, trauma, or surgical patients worldwide suffer from scarring that severely affects their quality of life and social functioning. In order to prevent and treat diseases related to abnormal scar hyperplasia, clinicians and researchers have adopted various methods, such as scar grinding, surgical resection, drug injection in scar tissue, cryotherapy, laser and so on. However, these methods can not effectively inhibit the abnormal proliferation of scars and improve the adverse effects of existing scars on patients. To date, there is no accepted gold standard for the effective treatment and improvement of abnormal scar tissue.

NCT ID: NCT06336044 Not yet recruiting - Wrinkle Clinical Trials

Pre-marketing Clinical Trial to Evaluate the Safety and Efficacy of the Filler of Hyaluronic Acid Recombinant Collagen

Start date: May 2024
Phase: N/A
Study type: Interventional

Study to validate the safety and efficacy of the Hyaluronic Acid +Collagen filler 20 patients will undergo through 3 visits one to asses the health and apply the filler one after 4 weeks to check the results one after 16 weeks for the final check and results validation Safety assessed with analysis of the Adverse Events

NCT ID: NCT06247761 Not yet recruiting - Scar Clinical Trials

STASSH - TRAUMA - Absorbable vs Non-Absorbable Sutures in Trauma Hand Surgery

STASSH-TRAUMA
Start date: January 29, 2024
Phase: N/A
Study type: Interventional

An RCT will be set up to compare outcomes between two groups of hand surgery patients. These are: • Emergency hand surgery patients - randomized to either absorbable or non-absorbable suture. The primary outcomes investigated will be: • Infection occurrence The secondary outcomes will be: - Scar appearance at 1 week and 6-8 weeks (assessed from photographs and scar scoring scale) - Wound inflammation as a percentage of wound length at day 7 post surgery. - Patient symptoms at 1 week (assessed from patient questionnaire) - Patient symptoms at 6-8 weeks (assessed from patient questionnaire) - QDASH Score at 1 week (assessed from patient questionnaire) - QDASH score at 6-8 weeks (assessed from patient questionnaire) - Occurrence of other complications (assessed from the above photographs, the above questionnaires and from nurse and doctor led reports of wound breakdown and other complications)

NCT ID: NCT06191159 Not yet recruiting - Clinical trials for Postoperative Complications

Cosmetic Outcome of Electrocautery, Scalpel and PEAK PlasmaBlade for Surgical Breast Incisions

SCPPB
Start date: May 2024
Phase: N/A
Study type: Interventional

This study will compare the cosmetic scar result from the use of scalpel, electrocautery, and pulsed electron avalanche knife (PEAK) PlasmaBlade (PPB) for the initial skin incision for total mastectomy procedures without immediate breast reconstruction. It is hypothesized that there will be no significant difference in mastectomy scar cosmesis. The purpose and objectives of this study are: 1. To evaluate and compare the cosmetic scar result from the use of scalpel, standard electrocautery, or PEAK PlasmaBlade for initial incision for total mastectomy procedures without immediate breast reconstruction. 2. To inform future equipment choices for breast surgery including potential elimination of scalpels and their attendant risks.

NCT ID: NCT06171386 Not yet recruiting - Scar Clinical Trials

Microneedling vs Dermabrasion for Early Facial Scar Resurfacing

Start date: June 2024
Phase: N/A
Study type: Interventional

This study aims to determine whether microneedling or dermabrasion in the early post-operative period is superior in improving the appearance of surgical scars on the face.

NCT ID: NCT06119113 Completed - Scar Clinical Trials

Wound Infection Due to Suture Material in Caesarean Skin Incision and Evaluation of Cosmetic Results

Start date: January 1, 2023
Phase: N/A
Study type: Interventional

Our primary aim is to determine the most beneficial suture in order to reduce complications due to skin incision in common surgeries such as cesarean section, and our secondary aim is to evaluate the suture material used in terms of cosmetic results and participant preference.

NCT ID: NCT06117293 Recruiting - Acne Vulgaris Clinical Trials

Safety and Efficacy Evaluation of the Mosaic Ultra Device

Start date: February 21, 2023
Phase: N/A
Study type: Interventional

Evaluate the Safety and Efficacy of the Mosaic Ultra 1550nm system for the treatment of skin tone and texture, facial rejuvenation, photoaging, wrinkles, scars, stretch marks, acne vulgaris and hair loss.

NCT ID: NCT05838833 Recruiting - Scar Clinical Trials

Ointment to Prevent Scar After Thyroidectomy

Start date: February 14, 2023
Phase: Phase 2
Study type: Interventional

The goal of this study is to evaluate the efficacy and Safety of INV-001 administration for the prevention of scar after thyroidectomy. Participants will be asked to apply ointment on their scar for 12 weeks.