SARS-CoV-2 Transmission in Belgian Primary Schools of the Federation Wallonia - Brussels: An Epidemiological Pilot Study

SARS-CoV-2 Infection Clinical Trial

— DYNAtracs  

Official title:

SARS-CoV-2 Transmission in Belgian Primary Schools of the Federation Wallonia - Brussels: An Epidemiological Pilot Study

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT05046470
• Other study ID #: 2020/16NOV/552
• Secondary ID: ISRCTN16837012
• Status: Active, not recruiting
• Start date: January 14, 2021
• Est. completion date: January 14, 2025

Study information

• Verified date: February 2023
• Source: Université Catholique de Louvain
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The investigators hypothesize that children are less likely to become infected in the school environment, compared to the household or outside the school setting. Primary schools do not play a major role in SARS-CoV-2 spreading. They hypothesize that incidence level in schools is mainly a consequence of community transmission. The incidence level in household and that the secondary attack rate in schools remains at least 5 times lower that the transmission level in households.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 1233
• Est. completion date: January 14, 2025
• Est. primary completion date: January 14, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 6 Years and older

Eligibility

Inclusion Criteria:

• All children and school attenders from selected schools was invited to participate

Exclusion Criteria:

• Refusal to provide written informed consent before enrolment

Related Conditions & MeSH terms

• COVID-19
• SARS-CoV-2 Infection

Locations

Country	Name	City	State
Belgium	UCLouvain	Brussels

Sponsors (3)

Lead Sponsor	Collaborator
Université Catholique de Louvain	Université Libre de Bruxelles, University of Liege

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Infection of a child with SARS-CoV-2 secondary to a classmate	Time varying number and proportion of children infected with SARS-CoV-2 secondary to an asymptomatic infected classmate (transmission rate inside school with the child being the infector).	6 weeks
Primary	Infection of an adult school-attender with SARS-CoV-2 secondary to an infected child	Time varying number and proportion of adult school-attenders infected with SARS-CoV-2 secondary to an asymptomatic infected child (transmission rate inside school but from a child to an adult).	6 weeks
Primary	Infection of a child with SARS-CoV-2 secondary to an adult school attender	Time varying number and proportion of children infected with SARS-CoV-2 secondary to an infected adult school-attender (transmission rate inside school but from an adult to a child)	6 weeks
Primary	Infection of a child with SARS-CoV-2 secondary to a contact outside the school, including the household	Time varying number and proportion of children infected with SARS-CoV-2 secondary to a household contact or outside the school (transmission rate from in community).	6 weeks

External Links

•   Protocol
•   Study website