Prevalence of Two Major Geriatric Syndromes: Sarcopenia and Frailty

Sarcopenia Clinical Trial

Official title:

Prevalence of Two Major Geriatric Syndromes in Community- Dwelling Older Adults: Sarcopenia and Frailty

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04146844
• Other study ID #: GoztepeTRH1
• Status: Completed
• Start date: December 15, 2020
• Est. completion date: April 25, 2021

Study information

• Verified date: May 2021
• Source: Goztepe Training and Research Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Sarcopenia and frailty are two major syndromes in older adults. They are shown to be associated with low levels of functioning and higher rates of morbidity and mortality. In this study, we aim to report the prevalence of sarcopenia and frailty by using simple assessment methods such as SARC-F and FRAIL, respectively.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 500
• Est. completion date: April 25, 2021
• Est. primary completion date: April 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Being at the age of 65 or older

Exclusion Criteria:

• <24 points on Mini-Mental State Examination

• 12 points or higher on Geriatric Depression Scale

Related Conditions & MeSH terms

• Frailty
• Frailty Syndrome
• Sarcopenia
• Syndrome

Locations

Country	Name	City	State
Turkey	Umraniye Education and Research Hospital	Istanbul

Sponsors (3)

Lead Sponsor	Collaborator
Goztepe Training and Research Hospital	Istanbul Medeniyet University, Umraniye Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	SARC-F	SARC-F is a rapid tool to assess sarcopenia in elderly. It is considered indicative sign of sarcopenia if the person scores 4 points or higher out of 10 points.	5 minutes
Primary	FRAIL	The FRAIL scale (Fatigue, Resistance, Ambulation, Illnesses, & Loss of Weight) is a simple questionnaire of frailty syndrome for older adults. If a patient scores 3-5 points over a total score of 5 points in the FRAIL, he is considered as frail.	5 minutes
Secondary	Study of Osteoporotic Fracture (SOF) Criteria for Frailty	SOF is another index for measuring frailty. 2 or 3 points out of 3 points are considered as cut-off points for frailty.	5 minutes
Secondary	Charlson Comorbidity Index	For comorbidity assessment	5-10 minutes
Secondary	Rapid Assessment of Physical Activity (RAPA)	For the assessment of physical activity level	10 minutes
Secondary	Mini-Nutritional Assessment (MNA)	Assessment of nutritional status	10 minutes
Secondary	Katz Index of Independence in Activities of Daily Living	Assessment of activities of daily living	10 minutes
Secondary	Lawton -Brody Instrumental Activities of Daily Living Scale	Instrumental activities of daily living assessment	10 minutes
Secondary	Mini-Mental State Examination	Mini-Mental State Examination	15 minutes
Secondary	Blood Sample Analysis	A blood sample analysis will be performed to investigate the relationship between blood parameters, sarcopenia and frailty.	5 minutes
Secondary	Geriatric Depression Scale- Short Form	Assessment of depression	10 minutes