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Salpingectomy clinical trials

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NCT ID: NCT05374720 Recruiting - Hysterectomy Clinical Trials

Analysis of the Molecular Composition of Tubal Cilia in Patients With or Without Ectopic Pregnancy

CILTUBE
Start date: October 1, 2022
Phase: N/A
Study type: Interventional

Primary Ciliary Dyskinesia associated with abnormalities of lateralization of organs (with existence of a situs inversus in 50% of cases) and secondary fertility disorders related in humans to abnormalities of mobility of sperm but very little data on the structure and function of tubal cilia in women

NCT ID: NCT05300711 Recruiting - Colorectal Surgery Clinical Trials

Preventing Ovarian Cancer Through Oportunistic Salpingectomy at the Time of Colorectal Surgery

Start date: June 20, 2022
Phase: N/A
Study type: Interventional

This study aims to evaluate the feasibility, safety and cost-effectiveness of opportunistic salpingectomy (OS-the removal of the fallopian tubes) at the time of colorectal surgery to prevent ovarian cancer. Ovarian cancer is the fifth cause of cancer-related mortality in females in Canada. OS can prevent the most common and lethal type of ovarian cancer, high grade serous carcinoma (HGSC). OS during gynecologic surgery (hysterectomy or instead of tubal ligation) is safe and effective. However, rates of hysterectomies and tubal sterilization are decreasing. This research team aims to extend the prevention of ovarian cancer by expanding to offer OS during other surgeries in the pelvis where fallopian tubes are accessible, beginning with colorectal surgery. This study will examine: 1) the feasibility of OS at the time of colorectal surgery; 2) the safety of OS at the time of colorectal surgery; 3) the cost-effectiveness of OS at the time of colorectal surgery. The hypothesis is that OS will be well accepted by individuals with fallopian tubes undergoing colorectal surgery, and that the vast majority (around 90 percent) of attempts to remove both fallopian tubes will be successful. It is expected that there will be 10-20 minutes additional operating room time for completing OS and that there will be no increased risk of complications when OS is included in a colorectal surgery. The researchers also hypothesize that OS at the time of colorectal surgery will be cost-effective because of the reduced number of ovarian cancer cases and associated treatment costs.

NCT ID: NCT05228938 Terminated - Salpingectomy Clinical Trials

vNOTES Salpingo-oophorectomy or Bilateral Salpingectomy Compared With Laparoscopic.

Start date: May 29, 2022
Phase: N/A
Study type: Interventional

Objective: To compare the vNOTES approach versus conventional laparoscopic approach used in elective Salpingo-oophorectomy surgery for benign disease or bilateral salpingectomy for sterilization. Study design: Prospective cohort, randomized controlled trial. Study population: Planned Salpingo-oophorectomy for benign disease or bilateral salpingectomy for sterilization. Primary outcome - Adherence to planned surgical route, intra-operative parameters & complications, post-operative parameters & complications, rate of satisfaction.

NCT ID: NCT04757922 Enrolling by invitation - Menopause Clinical Trials

Stop Ovarian Cancer Young; Effect of the Opportunistic Salpingectomy on Age of Menopause

STOPOVCAyoung
Start date: March 1, 2021
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to evaluate the long-term safety of on the onset of menopause.

NCT ID: NCT04324034 Recruiting - Salpingectomy Clinical Trials

vNOTES Transvaginal Endoscopic Surgery Versus Laparoscopy

NOTRANDO
Start date: June 3, 2021
Phase: N/A
Study type: Interventional

The feasibility and safety of laparoscopy are no longer to be demonstrated, especially in the field of gynecology, but this technique often causes post-operative pain. New techniques are being developed to overcome the inconvenience of laparoscopy, notably endoscopic transluminal surgery using a natural orifice (NOTES). It avoids incisions and therefore scarring, and could reduce post-operative pain. It is now developing in the field of transvaginal gynecology (vNOTES). This study is the first prospective randomized study comparing the vNOTES technique to laparoscopy with postoperative pain assessment for performing a salpingectomy. The hypothesis is that the use of vNOTES transvaginal endoscopic surgery would reduce the post-operative pain of patients compared to laparoscopy in the context of a salpingectomy.

NCT ID: NCT03860805 Active, not recruiting - Laparoscopy Clinical Trials

SALpingectomy for STERilization (SALSTER)

SALSTER
Start date: April 3, 2019
Phase: N/A
Study type: Interventional

The SALSTER study is a register-based randomized clinical trial (R-RCT) that examines if laparoscopic salpingectomy instead of tubal ligation, as a contraceptive method, has no increased risk for complications and has no negative impact on ovarian function.

NCT ID: NCT03830502 Completed - Salpingectomy Clinical Trials

Driving Factors of Decision Making for Prophylactic Salpingectomy Versus Tubal Ligation at the Time of Cesarean Section

Start date: February 10, 2019
Phase:
Study type: Observational

Prophylactic (Opportunistic) salpingectomy is a cost-effective strategy recommended for reducing the risk of ovarian cancer at the time of gynecologic surgery in women who have completed childbearing. Similar evidence for cesarean section is growing. However, salpingectomy refers to the surgical removal of a female reproductive organ. Some women may have hesitations about salpingectomy with regard to religious concerns, reduced self-image, tubal reanastomosis or lack of knowledge. The investigators aimed to explore the underlying factors that motivate women for either decisions.

NCT ID: NCT03322605 Not yet recruiting - Salpingectomy Clinical Trials

Residual Tubal Tissue on the Ovarian Surface Following Salpingectomy With Laparoscopy and Laparotomy

Start date: March 1, 2018
Phase: N/A
Study type: Observational

Patients who undergo salpingo-oophorectomy +/- hysterectomy (laparoscopic or laparotomy) for benign indications, early cervical cancer or low-risk endometrial cancer will be included. Patients with other pelvic malignancies, previous bilateral salpingectomy or bilateral oophorectomy and excessive adhesions will be excluded. Laparoscopy and laparotomy groups will be compared in terms of fibril tissue remnants on the ovarian surface.

NCT ID: NCT03187327 Completed - Hysterectomy Clinical Trials

Feasibility of Opportunistic Salpingectomy at the Time of Vaginal Hysterectomy for Benign Pathology

FPS
Start date: September 2013
Phase: N/A
Study type: Observational

In this prospective study, patients who underwent vaginal hysterectomy with salpingectomy or salpingo-oophorectomy were included. The objective of this study is to assess the feasibility of prophylactic salpingectomy during vaginal hysterectomy for benign pathology and the prevalence of occult tubal lesions. The hypothesis is that prophylactic salpingectomy during vaginal hysterectomy for benign pathology present a low failure rate and it makes it possible to avoid the appearance of a certain number of ovarian cancers. The prevalence of bilateral salpingectomy with or without ovariectomy and the prevalence of histopathological and immunohistochemical (p53 expression) abnormalities were evaluated.

NCT ID: NCT02165709 Completed - Clinical trials for Prevention & Control

Cohort Study of Risk Reducing Salpingectomy

RRS
Start date: June 2014
Phase: N/A
Study type: Interventional

Women undergoing surgical sterilization will be interested in risk reducing salpingectomy, and surgeons performing the procedure will be able to successfully complete the salpingectomy.