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Safety Issues clinical trials

View clinical trials related to Safety Issues.

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NCT ID: NCT06173479 Active, not recruiting - Health Behavior Clinical Trials

Health Belief Model-Based Educational Intervention on Safe Pesticide Use and Biomarkers in Agricultural Workers

HeBSaPU
Start date: November 11, 2023
Phase: N/A
Study type: Interventional

Brief Summary: Purpose: This clinical trial aims to investigate the effect of educational interventions (HeBSaPU) based on the Health Belief Model on safe pesticide use and biomarkers among greenhouse agricultural workers. The main questions it aims to answer are; 1. Compared to the control group, HeBSaPU affects safe pesticide use practices in greenhouse agricultural workers. 2. Compared to the control group, HeBSaPU affects safe pesticide use health beliefs in greenhouse agricultural workers. 3. Compared to the control group, HeBSaPU affects pesticide exposure determined by urine samples in greenhouse agricultural workers. Participants took educational interventions based on Health Belief Model (HBM) sub-dimensions; including educational posters, free personal protective equipment (PPE) incentives, short reminder messages, and demonstration components about correct PPE usage.

NCT ID: NCT06141109 Recruiting - Safety Issues Clinical Trials

Treatment of MB07133 Plus Sintilimab in Patients With Hepatocellular Carcinoma

MB07133
Start date: January 18, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

An open-label, multi-dose clinical trial design was used to investigate the combination of MB07133 injection combined with Sintilimab in the treatment of primary liver cancer in phase I/IIa studies, including two phases of dose escalation and dose expansion,in order to evaluate the safety and efficacy of MB07133 injection combined with Sintilimab.

NCT ID: NCT06141096 Recruiting - Safety Issues Clinical Trials

MB07133 for the Treatment of Patients With Unresectable Hepatocellular Carcinoma

MB07133
Start date: January 17, 2020
Phase: Phase 2
Study type: Interventional

A randomized, open, multicenter clinical trial design was adopted, planned to be conducted in three stages, with 91 participants expected to be included in the study to evaluate the efficacy, tolerance, and safety of different doses of MB07133 in the treatment of unresectable advanced primary liver cancer.

NCT ID: NCT06123611 Enrolling by invitation - Safety Issues Clinical Trials

Pediatric Trauma Centers RE-AIM at Gun Safety

ACTFAST
Start date: February 25, 2024
Phase: N/A
Study type: Interventional

Universal firearm injury and violence prevention counseling of parents and patients has been recommended by multiple national organizations for over a decade, yet clinicians rarely deliver this counseling. Barriers to its implementation must be addressed in order to effectively deliver firearm related injury prevention efforts. This study will implement a universal firearm injury prevention initiative within a national cohort of three pediatric trauma centers. The investigator's long-term goal is to demonstrate best practices for pediatric trauma center-based firearm injury prevention strategies that promote safe storage practices and reduce firearm related injury and death. This research will test the effectiveness of a comprehensive training strategy for improving the implementation of a universal firearm injury prevention effort, ACTFAST (Adopting Comprehensive Training for FireArm Safety in Trauma centers), to 1) increase the adoption, implementation and sustainability of a universal firearm injury prevention initiative within participating pediatric level 1 trauma centers; 2) increase firearm safety knowledge, attitudes and safe firearm storage practices among parents of pediatric trauma patients and youth patients treated within participating pediatric level 1 trauma centers, and 3) increase trauma center clinicians' firearm safety knowledge and confidence in delivering a firearm safety intervention.

NCT ID: NCT06117800 Completed - Safety Issues Clinical Trials

Effect of Evidence Based Teamwork System on Patient Safety Culture

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

This study aims to evaluate the effect of evidence-based teamwork system on patient safety culture among newly graduate nurses at Main Mansoura University Hospital

NCT ID: NCT06114641 Recruiting - Safety Issues Clinical Trials

Effectiveness & Safety of Ovine Enoxaparin Sodium to Originator Enoxaparin in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients: a Multicenter, Non-randomized, Open-label, Non-inferiority Trial

Start date: June 1, 2023
Phase: Phase 4
Study type: Interventional

The aim of this study is evaluating safety and effectiveness of Ovine Enoxaparin Sodium in Non-ST-Segment Elevation Acute Coronary Syndrome (NSTEACS) Patients

NCT ID: NCT06095804 Not yet recruiting - Safety Issues Clinical Trials

Clinical Pilot Study of the Percutaneous Ultrasound Jejunostomy Procedure

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the feasibility and performance of the Percutaneous Ultrasound Jejunostomy (PUJ) procedure that utilizes a novel device (PUMA-J System) in conjunction with widely available ultrasound technology and endoscopic guidance. The procedure will be performed in up to 10 eligible subjects. Patients will be followed for 2 days following performance of PUJ to assess for potential complications.

NCT ID: NCT06087913 Recruiting - Safety Issues Clinical Trials

Safety and PK Multi-dose Study of TAF/EVG Vaginal Insert

Start date: November 8, 2023
Phase: Phase 1
Study type: Interventional

MATRIX-001 will examine the safety, PK, modeled PD, and acceptability of inserts containing the combination of TAF and EVG applied vaginally, daily for 3 days, then every other day for 14 days. The inserts are ultimately intended to be the basis of an event-driven, on-demand method for prevention of HIV and HSV sexual infection.

NCT ID: NCT06076512 Recruiting - Chronic Pain Clinical Trials

Pain Clinic Provides Public Health Safety

Start date: February 2, 2018
Phase:
Study type: Observational

Chronic pain is associated with psychological disorders; which may affect a patient's socioeconomic, legal, domestic, and employment situations. This prospective observational study evaluates the impact of pain management on patients' health, social, economic, and employment status. It explores the impact of pain clinic services on patients' mental health, family health, public health, road safety, addiction situation, public safety, injury rehabilitation and employment situation.

NCT ID: NCT06053853 Completed - Safety Issues Clinical Trials

Post Marketing Surveillance of Diphtheria Antitoxin (DAT)

Start date: January 31, 2023
Phase: Phase 4
Study type: Interventional

The aim of this study is to evaluate the safety profile of Diphtheria Antitoxin