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Rupture clinical trials

View clinical trials related to Rupture.

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NCT ID: NCT02469519 Completed - Premature Birth Clinical Trials

Impact of a Booster Course of Antenatal Steroids on Neonatal Outcome in Patients With Premature Rupture of the Membranes

ACSinPROM
Start date: March 3, 2016
Phase: Phase 2/Phase 3
Study type: Interventional

This trial hopes to prospectively evaluate the impact of one versus two courses of antenatal steroids on the incidence of major neonatal morbidity in pregnant women with pre-labor premature rupture of the membranes.

NCT ID: NCT02463760 Completed - Clinical trials for Aortic Aneurysm, Abdominal

Predicting Rupture of AAA by Anatomic and Hemodynamic Markers

Start date: August 2015
Phase:
Study type: Observational

The purpose of the study is to investigate imaging findings, which can help us to predict factors contributing to abdominal aortic aneurysm growth and rupture.

NCT ID: NCT02422004 Recruiting - Clinical trials for Achilles Tendon Rupture

Healing of Human Achilles Tendon Rupture

Start date: August 2012
Phase: N/A
Study type: Interventional

The overall aim of this project is to investigate the healing processes of human tendon after suturing a ruptured Achilles tendon, and more specifically to determine the optimal loading pattern of the tendon during the rehabilitation period to ensure complete and good recovery of tendon structure and function. The investigators hypothesize that restricting early weight bearing and only allowing for passive stretching in the early phase of tendon healing will ensure better tissue regeneration and thereby prevent chronic tendon elongation and improve tendon tissue recovery and the clinical outcome.

NCT ID: NCT02420353 Completed - Clinical trials for Rupture of Anterior Cruciate Ligament

Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears

Start date: May 2015
Phase: Phase 2
Study type: Interventional

Anterior cruciate ligament (ACL) tears are among the most frequent traumatic knee injuries that occur in physically active individuals. Despite advances in minimally invasive surgical reconstruction techniques and aggressive rehabilitation, this atrophy and loss of strength can persist even after patients return to full activity and can place them at considerable risk for re-injury and developing osteoarthritis (OA). The design of new therapeutic interventions to prevent muscle atrophy is needed to advance the care of patients who suffer from ACL injuries. The growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis plays an important role in promoting muscle growth and protecting muscle from atrophy. While GH therapy has shown promise in protecting immobilized muscle from various models of disuse atrophy, it remains unknown whether GH can help to restore strength and protect against the loss in strength that occurs after ACL tear. GH therapy may help to accelerate the safe return to play of patients that suffer ACL tears, and help to prevent the long-term OA and reduction in quality of life that occur after these traumatic knee injuries.

NCT ID: NCT02386644 Completed - Clinical trials for Preterm Premature Rupture of the Membranes

Transperineal Ultrasonography and Premature Rupture of Membranes

Start date: February 2015
Phase: N/A
Study type: Interventional

This study's aim is to evaluate diagnostic accuracy of transperineal ultrasound assessment compared with speculum examination, nitrazine and placental micro globulin-1 tests.

NCT ID: NCT02383914 Completed - Clinical trials for Subscapularis Tendon Rupture

Clinical Study on Diagnostics and Outcome of Ruptures of the Subscapularis After Arthroscopic Refixation

Start date: March 2014
Phase:
Study type: Observational

The purpose of the trial is to optimize the diagnostics of subscapularis tendon tears and as the circumstances require to found a new classification. The prime objective is a comparison of the conclusive of the clinic check-up, the sonographic and magnetic resonance tomography findings. The secondary objective is to detect the correlation of the outcome with the age , the gender, the pathogenesis and attendant injuries.

NCT ID: NCT02380560 Recruiting - Clinical trials for Fetal Membranes, Premature Rupture

Myometrial Thickness as a Predictor for the Latency Interval in PPROM

Start date: March 1, 2018
Phase: N/A
Study type: Observational

100 women divided into 3 groups: - Group I: included 50 women with preterm premature rupture of membranes (PPROM, n=50) with gestational age from 24 to 34 weeks. - Group II: included 25 term non-labor control (T-CTR, n=25) with gestational age from 37 to 41 weeks. - Group III: included 25 preterm non-labor control (P-CTR, n=25) with gestational age from 24 to 34 weeks.The myometrial thickness at 4 different sites9: a) The lower uterine segment (LUS): 2cm above the reflection of the full urinary bladder (b)The anterior wall: 1cm above the maternal umbilicus. (c)Fundus: by placing the scan probe perpendicularly above the uterine fundus so that the entire curvature of the uterus was visualized. (d)The posterior wall: through using the maternal abdominal aortic pulsation as an anatomic marker. At least 3 measurements were obtained at each site and averaged. The latency interval is determined in each of the 3 groups.

NCT ID: NCT02374775 Active, not recruiting - Clinical trials for Myocardial Infarction

Exploring the MEchanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and computationaL Fluid Dynamic

EMERALD
Start date: September 2014
Phase: N/A
Study type: Observational

The EMERALD trial is a multinational, multicenter study. The patients presented with AMI/definite evidence of plaque rupture and had underwent coronary CT angiography from 1 month to 2 year prior to the event will be retrospectively searched. Plaques in the non-culprit vessels will be regarded as internal control to the ruptured plaque in the culprit vessel.

NCT ID: NCT02369601 Recruiting - Clinical trials for Fetal Membranes, Premature Rupture

PROMComplete for Determination of Rupture of Fetal Membranes

(PROMComplete
Start date: August 2015
Phase:
Study type: Observational

Premature rupture of membranes refers to the rupture of the fetal membranes prior to the onset of labor. Premature rupture of membranes is associated with a number of neonatal and maternal complications including an increased incidence of perinatal mortality and intra-amniotic infection. There is a need for improved diagnostic testing because of limitations of the current methods. PRO-MComplete is an immunochromatographic test that detects insulin growth factor binding protein 1 and alpha-fetoprotein in vaginal fluid as an indicator of membrane rupture.

NCT ID: NCT02348437 Completed - Radius Fractures Clinical Trials

Repair vs Non-repair of the Pronator Quadratus Muscle in Distal Radius Fractures. RCT.

Start date: February 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the functional outcome of repairing the pronator quadratus (PQ) muscle in subjects operated for a distal radius fracture (DRF) with volar locked plating.