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Rupture clinical trials

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NCT ID: NCT03106311 Completed - Clinical trials for Premature Rupture of Membrane

The Use of Quantitative Pregnancy Test in Amniotic Fluid as a Diagnostic Tool for Rupture of Fetal Membranes

Start date: April 10, 2017
Phase: N/A
Study type: Interventional

Two groups will be recruited. The first group are pregnant ladies that have unequivocal rupture of fetal membranes that is diagnosed by seeing the amniotic fluid leakage in the vagina. The second group are normal pregnant ladies without rupture of membranes. both groups will be tested by taking vaginal washing fluid. Quantitative and qualitative pregnancy tests will be measured in this fluid.

NCT ID: NCT03097744 Completed - Meniscus Lesion Clinical Trials

Predictors of Early Success From Circumferential Compression STITCH Meniscal Repairs

STITCHRetro
Start date: February 1, 2017
Phase:
Study type: Observational

This is a retrospective study of meniscal tear repairs at least one-year post repair status. All patients were treated with Ceterix NovoStitch devices. The primary objectives of this study are to assess the clinical repair success rate via reoperation and PROs at greater than 12 months.

NCT ID: NCT03060473 Recruiting - Clinical trials for Preterm Premature Rupture of Membranes (PPROM)

Treatment of ppROM With Erythromycin vs. Azithromycin Trial

TREAT
Start date: February 23, 2017
Phase: Phase 3
Study type: Interventional

Preterm premature rupture of membranes (PPROM) complicates 4% of pregnancies annually. This pregnancy complication is a major contributor to preterm births and results in neonatal morbidity and mortality. The current standard of care for PPROM subjects between the gestational age of 24 weeks and 0 days and 33 weeks and 6 days, is to administer ampicillin and erythromycin for a total of 7 days. Erythromycin can cause GI upset and some subjects do not tolerate this regimen over the course of 7 days. In addition, there is a national shortage of erythromycin, and published expert opinion proposed to use a second-generation macrolide (azithromycin) instead of erythromycin. Azithromycin can be taken once daily, is cheaper than erythromycin and has less GI upset adverse effects. The investigators' objective is to compare the effectiveness of the 2 regimens in prolonging pregnancy after PPROM. The investigators' working hypothesis is that there is no measurable difference in the primary outcome between the group randomized to the azithromycin regimen versus the group randomized to the erythromycin regimen.

NCT ID: NCT03052686 Completed - Anomaly Uterus Clinical Trials

Retrospective Study of 110 Cases of Uterine Rupture to Determine Obstetric and Neonatal Complications

RUVO
Start date: January 2000
Phase: N/A
Study type: Observational

This study has for objective to collect medical data from patients with uterine rupture at the childbirth.

NCT ID: NCT03039582 Completed - Perineal Tear Clinical Trials

Short Anovaginal Distance is Associated With Obstetric Anal Sphincter Rupture

AVD and OASR
Start date: September 1, 2014
Phase: N/A
Study type: Observational

Anovaginal distance measured by palpation and perineal ultrasound are similar.

NCT ID: NCT03025581 Not yet recruiting - Clinical trials for Premature Rupture of Fetal Membranes

Does Nipple Stimulation Shorten Time to Vaginal Birth in Women With Term PROM?

NIPROM
Start date: January 2017
Phase: N/A
Study type: Interventional

Premature Rupture of Membranes (PROM) is defined as the rupture of membranes before the onset of regular uterine contractions. PROM occurs in approximately 10% of all pregnancies (ranging from 2.7% to 17%), with 60% to 80% of cases occurring at term. Approximately 90% of patients' experience PROM enter spontaneous labor within 24 hours, but disagreement exists among health care providers on the optimal management of women with PROM, particularly the need for and timing of inductions. Nipple stimulation is a non-medical natural method for induction of labor. Previous studies demonstrated its effectiveness for initiating labor within 72 hours in women with favorable cervices. The actual mechanism by which such a technique results in cervical ripening is not well understood. In this study, we aim to assess the effectiveness of nipple stimulation in gravid women with term PROM choosing expectant management.

NCT ID: NCT02997345 Recruiting - Premature Birth Clinical Trials

PPROM Registry (Preterm Premature Rupture of Membranes)

Start date: July 2013
Phase:
Study type: Observational [Patient Registry]

Preterm Premature Rupture of Membranes (PPROM) before 37 weeks of pregnancy is responsible for 40% of preterm births in the United States. The PPROM Registry aims to identify possible causes of PPROM, evaluate trends in expectant management, measure maternal and fetal care, and to review short term and long term outcomes of affected pregnancies and births.

NCT ID: NCT02996253 Active, not recruiting - Clinical trials for Achilles Tendon Rupture

Endoscopic Transfer of Flexor Hallucis Longus Tendon for Chronic Achilles Tendon Rupture

Start date: December 2015
Phase:
Study type: Observational

The transfer of Flexor Hallucis Longus (FHL) in the management of chronic Achilles tendon ruptures has demonstrated good functional outcome, but an extensive surgical field at a vulnerable location may lead to increased risk for soft tissue problems. The arthroscopic FHL transfer may reduce the risk for soft tissue problems. Functional outcome parameters are investigated, wound/soft tissue complications registered.

NCT ID: NCT02993679 Completed - Clinical trials for Cruciate Ligament Rupture

Stability of the Knee Joint After Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction

Start date: July 2014
Phase: N/A
Study type: Interventional

The objective of this randomised cohort study was to evaluate the knee rotational stability after the single-bundle ACL reconstruction (SB) with addition of the ALL reconstruction and to compare it with the double-bundle ACL reconstruction technique (DB) and to analyse when the ALL is necessary to reconstruct.

NCT ID: NCT02977910 Not yet recruiting - Ankle Fractures Clinical Trials

Treatment Strategy of Ankle Fracture Combined With Deltoid Ligament Rupture

Start date: January 2017
Phase: N/A
Study type: Interventional

Ankle fracture is very common which is often combined with deltoid ligament injury. Although the incidence of deltoid ligament injury is high, but there is no unified and effective diagnosis method. Even whether the ankle fracture with deltoid ligament rupture needs surgical repair is still controversial. There is no high-level, multi-center, large sample, long-term follow-up clinical evidence to prove whether the repair of deltoid ligament is necessary or not. The main content of the project: 1 Achieve accurate classification of deltoid ligament rupture with intraoperative exploration. 2 Study the surgical indications and treatment guidelines by comparative study.