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Rupture clinical trials

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NCT ID: NCT01633294 Completed - Chorioamnionitis Clinical Trials

Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term

Start date: October 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The aims of this study are to determine whether antibiotics administered routinely in women presenting with premature rupture of membranes later than the 37+0 weeks of gestation can alter the rate of maternal and neonatal infection and to compare these rates between prompt (< 12 hour) and delayed (≥ 12 hour) induction in the group of patients not submitted to antibiotic prophylaxis.

NCT ID: NCT01632774 Completed - Aortic Rupture Clinical Trials

Analysis of Risk Factors for Death After Blunt Traumatic Rupture of the Thoracic Aorta

Start date: January 1990
Phase: N/A
Study type: Observational

Aortic injuries after blunt thoracic trauma are compared to the great incidence of accidents relatively rare, but potentially serious leading to death at scene in most of the cases. The study was undertaken to delineate mortality and its risk factors on three different levels (pre-hospital, in-hospital and overall). Between 1990 and 2003, all consecutive patients and victims with traumatic aortic rupture were retrospectively analyzed by reviewing hospital and autopsy records.

NCT ID: NCT01616823 Completed - HIV Clinical Trials

Fetal HIV Transmission Risk and Duration of Membrane Rupture

Start date: January 2009
Phase:
Study type: Observational

In optimally managed HIV+ women with undetectable viral loads, who are on HAART and also receiving intrapartum IV ZDV, the risk of vertical transmission of HIV is independent of the length of time of rupture of membranes.

NCT ID: NCT01544387 Completed - Pregnancy Clinical Trials

Preterm Premature Rupture of Membranes (PPROM): Bed Rest Versus Activity Trial

BRAT
Start date: July 2010
Phase: N/A
Study type: Interventional

The objective of this study is to determine, through a randomized clinical trial, whether bed rest is helpful for the management of pregnancies complicated by preterm premature rupture of membranes (PPROM).

NCT ID: NCT01538030 Completed - Premature Rupture Clinical Trials

Perinatal Outcome After Premature Rupture of Membranes

Start date: May 2012
Phase: N/A
Study type: Observational

Premature rupture of membranes is an important cause of neonatal morbidity and mortality, mainly because of the complications associated with this pathology (oligohydramnios, cord compression or prolapse, infection). When rupture of the membranes occur the risk of cord compression increases but there is little evidence regarding this complication and amniotic fluid volume. The investigator's focus are the perinatal outcomes according to amniotic fluid volume (< 5 or >5).

NCT ID: NCT01503606 Completed - Clinical trials for Preterm Premature Rupture of Membrane

Duration of Antibiotics Treatment With Cefazolin and Clarithromycin in Women With Preterm Premature Rupture of Membrane

Start date: October 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the neonatal outcome and infant neurologic outcome whose mother were treated with cefazolin plus clarithromycin for one week or until delivery after preterm premature rupture of membrane.

NCT ID: NCT01470833 Completed - Clinical trials for Acute Achilles Tendon Rupture

Non-operative Treatment of Acute Achilles Tendon Rupture Using Dynamic Rehabilitation. Influence of Early Weight-bearing Compared With Non-weight-bearing

Start date: April 2011
Phase: N/A
Study type: Interventional

Acute achilles tendon rupture is relatively frequent (11 to 37 per 100,000). There are great social benefits in optimizing treatment and shortening recovery. There is no consensus concerning the best treatment of acute achilles tendon rupture. Traditionally, surgical treatment is considered superior, but more recent studies show evidence that non-operative treatment with early dynamic rehabilitation gives the same functional outcome with fewer side effects. Traditionally non-operative treatment involves non-weightbearing for 6 weeks. This is not evidence based rather due to tradition. It is well documented that mechanical load improves tendon healing in general and has no detrimental effect on the healing of operated achilles tendons. The objective of this randomized study is to compare early weight-bearing with non-weight-bearing following non-operative treatment of acutely ruptured Achilles tendons.

NCT ID: NCT01440348 Completed - Clinical trials for Rupture of Anterior Cruciate Ligament

Simultaneous Multiple Cruciate Ligament Reconstructions Using a Single Achilles Allograft

Start date: May 2011
Phase: Phase 4
Study type: Interventional

This study introduce cases of simultaneous multiple cruciate ligament reconstructions with a single free tendon Achilles allograft using new technique.

NCT ID: NCT01431248 Completed - Clinical trials for Preterm Premature Rupture of Membranes

PPROM Erythromycin Versus Azithromycin

PEACE
Start date: September 2011
Phase: N/A
Study type: Observational

Preterm Premature Rupture of Membranes (PPROM) is treated with an antibiotic, erythromycin or azithromycin, to prolong pregnancy. Erythromycin is taken for several days and can result in stomach upset in some patients, causing them to stop taking the medication. Therefore, azithromycin is often prescribed instead. Azithromycin is usually taken only once and stomach upset is not seen or greatly reduced. The goal of this study is to see if there is a difference between the antibiotic (azithromycin) compared to the antibiotic (erythromycin) in prolonging pregnancy in patients with Preterm Premature Rupture of Membranes (PPROM). The working hypothesis is that there is no difference in the clinical effectiveness between antibiotic regimens containing te macrolides azithromycin and erythromycin for prolonging latency in PPROM.

NCT ID: NCT01401179 Completed - Clinical trials for Preterm Premature Rupture of the Membranes

Antibiotics Study in Preterm Premature Rupture of the Membranes

PPROM
Start date: April 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the efficacy on maternal infection, chorioamnionitis and neonatal morbidity and mortality, and to review the evidence and provide recommendations on the use of antibiotics in PPROM.