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Rupture clinical trials

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NCT ID: NCT02993679 Completed - Clinical trials for Cruciate Ligament Rupture

Stability of the Knee Joint After Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction

Start date: July 2014
Phase: N/A
Study type: Interventional

The objective of this randomised cohort study was to evaluate the knee rotational stability after the single-bundle ACL reconstruction (SB) with addition of the ALL reconstruction and to compare it with the double-bundle ACL reconstruction technique (DB) and to analyse when the ALL is necessary to reconstruct.

NCT ID: NCT02939677 Completed - Gait, Unsteady Clinical Trials

Can Targeted Exercise Improve Knee Strength Following ACLR (RATE)

RATE
Start date: January 2017
Phase: N/A
Study type: Interventional

Anterior cruciate ligament reconstruction (ACLR) is high volume surgery, carried out in about 2800 patients annually in Denmark per year. ACLR patients (using hamstring auto-graft) have persistent hamstring strength deficiency when evaluated more than 1-2 years after ACL-reconstruction. The investigators have designed this randomized controlled trial (RCT) with the main purpose to investigate the effect of a targeted muscle strength exercise intervention on the neuromuscular rehabilitation of ACLR-patients compared with 'care-as- usual'. The study is designed as a prospective, superiority, parallel-group with balanced randomization (1:1) RCT (Level of evidence: II) with blinded allocation, and outcome assessment according to the CONSORT statement (Consolidated Standards of Reporting Trials). 50 patients with ACL reconstruction and persistent hamstring muscle deficiency, will be recruited at the outpatient clinic 1-year follow-up, and allocated to one of two 12 weeks' interventions, either a) the supervised progressive strength and neuromuscular exercise group (SNG) with supervised training twice weekly. Or b) the control group (CON) receiving patient education based on a home-based exercise regime of low intensity, defined as 'care as usual'. Outcome measures include, maximal isometric knee flexor muscle strength (primary outcome), knee extensor strength, and the Knee injury and Osteoarthritis Outcome Score (KOOS) (secondary outcomes). In addition, the following explorative outcomes will be investigated; hamstring to quadriceps strength ratios, the International Knee Documentation Committee Subjective Knee Form (IKDC), magnetic resonance imaging (MRI) to evaluate tendon regeneration of the hamstrings and finally kinetic/kinematic biomechanical outcomes of knee related functional tasks. To the investigators knowledge, this is the first RCT to investigate the efficacy of combined progressive resistance training and neuromuscular exercise in the late rehabilitation phase in patients demonstrating persistent limb-to-limb knee muscle asymmetry following ACLR. Reduced hamstring strength represents a potential risk factor for secondary ligament rupture and accelerated progression of osteoarthritis (OA). If deemed effective, the intervention paradigm introduced in this study may help to improve current treatment strategies.

NCT ID: NCT02901795 Completed - Clinical trials for Fetal Membranes, Premature Rupture

Early Detection of Chorioamnionitis in Preterm Premature Rupture of Membranes

AiRPM
Start date: November 2, 2018
Phase:
Study type: Observational

All included patients will have their fetal heart rate recording performed with an EDAN F3 fetal monitor that allowed the back up recording of the fetal heart rate beat to beat detection. Fetal heart rate variability analysis will be performed using Matalb® software.

NCT ID: NCT02878226 Completed - Maternal Mortality Clinical Trials

Outcomes of Uterine Rupture

Start date: August 2016
Phase:
Study type: Observational

Uterine rupture (UR) is a serious, life-threatening obstetric complication. UR is associated with an increased risk of maternal and perinatal morbidity and mortality, particularly in developing countries compared to developed countries. UR occurs mainly as a consequence of poorly managed labour

NCT ID: NCT02825641 Completed - Clinical trials for Medical Induction of Labor Affecting Newborn

Premature Rupture of Membranes With a Bishop Score<6: Comparison of Medical Induction/Expectant Management

Start date: August 1, 2016
Phase: N/A
Study type: Interventional

The study is intended to compare expectant management and on presentation labor induction in women with premature rupture of membranes. The means of labor induction and cervical ripening are either oxytocin or dinoprostone. Expectant management in this obstetrical state means waiting 24 hours from the onset of rupture of membranes and then commencing labor induction with either oxytocin or dinoprostone depending on the patient's obstetrical history and cervical condition. The investigators' hypothesis is that active management will lead to a higher rate of vaginal deliveries, a shorter interval between the time of rupture of membranes and the time of delivery, a lower rate of cesarean sections and a better obstetric result for the mother and the fetus/newborn.

NCT ID: NCT02817399 Completed - Clinical trials for Rupture of Anterior Cruciate Ligament

The Effect of Functional Electrical Stimulation

Start date: January 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to examine the short term effect of functional electrical stimulation treatment versus neuro-muscular electrical stimulation on gait quality for patient after anterior cruciate ligament reconstruction.

NCT ID: NCT02805751 Completed - Clinical trials for Achilles Tendon Rupture

Early Controlled Loading on Conservative Treated Achilles Tendon Ruptures

Start date: October 2015
Phase: N/A
Study type: Interventional

The purpose of this study is to measure the mechanical properties of the tendon after conservative treated Achilles tendon ruptures with or without early controlled loading. This is done in a randomized trial and the mechanical properties are measured using roentgen stereometric analysis (RSA). The hypothesis is that early weightbearing improves mechanical properties of conservative treated Achilles tendon ruptures without causing elongation of the tendon.

NCT ID: NCT02760875 Completed - Clinical trials for Achilles Tendon Rupture

Foot Pressure Mapping and Tendon Length After Nonoperative Treatment of Acute Achilles Tendon Rupture

Start date: January 2016
Phase:
Study type: Observational

Using a population of patients from another study, who was originally randomized to 2 different types of nonoperative treatment after an acute achilles tendon rupture, the length of the achilles tendon is examined using ultrasound, and foot pressure mapping is performed, 4-5 years after the injury.

NCT ID: NCT02760784 Completed - Clinical trials for Achilles Tendon Rupture

Medium Term Outcome of Nonoperative Treatment After Achilles Tendon Rupture.

Start date: January 2016
Phase: N/A
Study type: Observational

A total of 56 patients completed a previous study regarding non-operative treatment for acute achilles tendon rupture. This study consists of an additional follow up after 4-5 years depending on original date of injury.

NCT ID: NCT02754674 Completed - Clinical trials for Rupture of Anterior Cruciate Ligament

Comparison of Femoral Tunnel and Clinical Outcome Using Two Anterior Cruciate Ligament Reconstruction Techniques

Start date: May 2014
Phase: N/A
Study type: Interventional

1. Purpose :To compare of femoral tunnel placement, tunnel geometry and clinical outcome using two anterior cruciate ligament reconstruction techniques ; transportal technique with flexible reamer and single bundle outside in technique with remnant preservation. 2. Subjects: anterior cruciate ligament (ACL) injury 66 patients - Double bundle transportal technique with flexible reamer: 33 - Single bundle outside in technique with remnant preservation: 33