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Rupture clinical trials

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NCT ID: NCT06456814 Recruiting - Clinical trials for Intracranial Aneurysm

Epidemiological Insights Into the Formation, Progression, and Rupture of Intracranial Aneurysms: A Retrospective, Multi-Center Hospital-Based Study in China

Start date: January 1, 2010
Phase:
Study type: Observational

This is a retrospective, hospital-based and multi-center study aiming at investigating the potential exposures associated with the formation, progression, and rupture of intracranial aneurysms in Chinese population.

NCT ID: NCT06450912 Completed - Clinical trials for Acute Myocardial Infarction

Wall Strain Index Ratio as a Biomarker for Mechanical Complication of Hemorrhagic Myocardial Infarction

MIRON-STRAIN
Start date: June 1, 2022
Phase:
Study type: Observational

Hemorrhagic Myocardial infarctions are at high risk for mechanical complications including cardiac rupture. Prediction of vulnerable myocardial segments is an important step for the stratification of hemorrhagic MI patients. Wall motion index ratio is an important parameter to determine regions of high vulnerability within the 17-segment LV model of hemorrhagic MI.

NCT ID: NCT06443788 Recruiting - Clinical trials for Preterm Premature Rupture of Membrane

Trans-perineal Ultrasound in Assessment of PPROMs

Start date: February 15, 2024
Phase: N/A
Study type: Interventional

Accurate and timely diagnosis of preterm pre-labor rupture of membranes (PPROM) is important to prevent adverse maternal and fetal outcomes. Following a history of PPROM, physical examination should be performed in a way that minimizes the risk of infection using a speculum. This is important to confirm the diagnosis by visualizing the amniotic fluid passing from the cervical canal or pooling in the vagina. In addition to examining the cervix to assess its dilatation and effacement and look for umbilical cord prolapse or fetal prolapse. However, Pelvic exam is one of the most common anxiety provoking medical procedures that's why this study aims at using the transperineal ultrasound as a non-invasive, accurate, cost effective, applicable and readily available tool in assessment of PPROM with less patient anxiety and fear.

NCT ID: NCT06443736 Recruiting - Clinical trials for Perineal Laceration, Tear, or Rupture During Delivery

TRESPASS Clinical Study

Start date: April 19, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the superiority of a standardized perineal massage in the decrease in vagino-perineal lacerations.

NCT ID: NCT06434272 Not yet recruiting - Clinical trials for Achilles Tendon Rupture

Blood Flow Restriction Exercise in Patients With an Achilles Tendon Rupture

BEAN
Start date: August 1, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to gain insights into the effects of Blood Flow Restriction Exercise (BFRE) in patients with an acute Achilles tendon Rupture. The main questions it aims to answer are: Is BFRE an effective adjunct to usual care when compared with only usual care? When is the optimal timing for initiating BFRE: In the early treatment stage or at the later stage after hospital treatment? Participants will receive an intervention comprising 12 weeks of BFRE as an adjunct to usual care. - Either in the initial 1-12 weeks after Achilles tendon rupture, or - In the following 13-24 weeks after Achilles tendon rupture Researchers will compare the two groups at 13 weeks to compare BFRE to usual care, and at 25 weeks to compare the two time points for initiating BFRE (early vs. late).

NCT ID: NCT06430775 Recruiting - Clinical trials for Anterior Cruciate Ligament Injuries

Exploring Prolonged AMR in ACL Reconstructed Patients

Start date: October 15, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this observational study is to explore the significance of subject-reported outcomes and clinical parameters in relation to the occurence of prolonged presence of arthrogenic muscle responses (AMR) in anterior cruciate ligament (ACL) reconstructed patients. The main questions it aims to answer are: 1. Is there a link between the long-term occurence of AMR in ACL reconstructed patients and the level of kinesiophobia experienced before or after their ACL surgery? We hypothesize that ACL patients with higher levels of kinesiophobia are more likely to exhibit prolonged AMR as an unconscious reaction to protect their affected knee joint. 2. Is the long-term presence of AMR in ACL reconstructed patients linked to their subjective knee function and stability (at certain time points throughout their recovery)? Our hypothesis is that poorer subjective knee function and stability might be associated with the presence of prolonged arthrogenic muscle responses in ACL reconstructed patients. 3. Is the prolonged presence of AMR in ACL reconstructed patients linked to their pain levels (at certain time points throughout their recovery)? Our hypothesis is that ACL patients with higher pre- and/or postsurgical pain levels may exhibit a higher degree of long-lasting AMR. 4. Is the long-term presence of AMR in ACL reconstructed patients linked to clinical parameters such as swelling, isometrich quadriceps and hamstrings strength and knee range of motion (at certain time points throughout their recovery)? Our hypothesis is that ACL patients with poorer outcomes in terms of these clinical parameters may be more likely to exhibit prolonged AMR. Participants will: - Fill in the following questionnaires 1 week before surgery and at 1 and 3 months after surgery: - Demopgraphical information - Knee Injury and Osteoarthritis Outcome Score (KOOS) - Lysholm Score (only question 1) - Tegner Activity Scale (current activity level, pre-injury activity level and desired activity level after recovery) - Numeric Rating Score (NRS) for pain levels during the day & during the night - ACL-Return to Sport after Injury Scale (ACL-RSI) - Complete a testing protocol 5 months after their surgery, which includes bilateral electromyographical measurements of the hamstrings and quadriceps during jumping tasks and a quadriceps inhibition measurement using the interpolated twitch method to evaluate the presence of prolonged AMR.

NCT ID: NCT06420648 Recruiting - Clinical trials for Flexor Tendon Rupture

Controlled Active Motion vs Early Passive Mobilization for Flexor Tendons Repair

Start date: June 4, 2024
Phase: N/A
Study type: Interventional

a randomized controlled trial tends to compare 2 rehabilitation approaches - early passive mobilization (EPM) and controlled active motion (CAM) - that are commonly used in the treatment of post-surgical flexor tendon repair of the hand

NCT ID: NCT06418217 Recruiting - Clinical trials for Greater Trochanteric Pain Syndrome

Exercise and Patient Education for Patients With Lateral Hip Pain

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

This prospective cohort trial will investigate a progressive exercise protocol and patient education for patients with hip abductor tendon pathology. The primary outcome is patient reported pain measured by the revised Copenhagen Hip And Groin Outcome Score (HAGOS), that will be conducted at baseline and at a 12 week follow-up.

NCT ID: NCT06398015 Recruiting - Clinical trials for Rupture of Hip Abductor Tendon (Disorder)

Hip Abductor Tendon Repair Versus Sham Surgery

Start date: May 1, 2024
Phase: N/A
Study type: Interventional

This study will examine the effectiveness of open surgical reconstruction in the treatment of patients with hip abductor tendon tears. Patients will be randomly allocated to either the open surgical reconstruction or to a open surgical sham procedure. The primary outcome is patient reported pain measured by the revised Copenhagen Hip And Groin Outcome Score (HAGOS), which will be conducted pre-surgery and at three and six months post-surgery. The six-month follow-up is the primary endpoint.

NCT ID: NCT06396078 Not yet recruiting - Preterm Birth Clinical Trials

Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)

Start date: August 1, 2024
Phase: Phase 4
Study type: Interventional

To conduct an unblinded pragmatic randomized controlled trial (pRCT) "Improvement of PPROM Management with Prophylactic Antimicrobial Therapy (iPROMPT)" of a seven-day course of ceftriaxone, clarithromycin, and metronidazole versus the current standard of care of a seven-day course of ampicillin/amoxicillin and azithromycin or erythromycin to prolong pregnancy and decrease adverse perinatal outcomes among hospitalized pregnant individuals undergoing expectant management of PPROM <34 weeks.