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Rotator Cuff Injuries clinical trials

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NCT ID: NCT03148353 Completed - Clinical trials for Shoulder Impingement

Standardized and Modified Corticosteroid Subacromial Injection for Shoulder Impingement Syndrome

SMCSINJ
Start date: May 30, 2017
Phase: N/A
Study type: Interventional

Subacromial injection is a useful procedure to counteract shoulder impingement syndrome. With the aid of high‐resolution ultrasound, the needle can be introduced precisely into the subacromial/subdeltoid bursa located between the acromion above and the supraspinatus tendon below. The standardized method allows the injectate to distribute along the subdeltoid bursa, further reliving pain from subacromial/subdeltoid impingement. In a substantial part of shoulder pain patients, it is common to accompany pain along the bicipital groove, which the biceps long head tendon courses through. The biceps long head tendon is attached to the superior labrum of the glenoid cavity and acts as the second important structure to prevent upward migration of the humeral head, following the supraspinatus tendon. Overuse injury of the biceps tendon is a likely cause of anterior shoulder pain. Concomitant administration of medication into the subacromial bursa and biceps tendon sheath is theoretically more effective than injection to the subacromial bursa only because the formal procedure targets two vulnerable structures in shoulder impingement syndrome at once. Regarding the standard ultrasound‐guided subacromial injection. Therefore, we will conduct a randomized controlled trial investigating the effectiveness of standard subacromial injection in comparison with a novel approach simultaneously injecting the subacromial bursa and biceps tendon sheath.

NCT ID: NCT03111147 Completed - Clinical trials for Rotator Cuff Tear Arthropathy

Impact of Humeral Component Version on Outcomes Following RTSA

Start date: May 12, 2017
Phase: N/A
Study type: Interventional

The proposed study is a prospective, single-blinded, randomized trial to investigate the impact of humeral component version on shoulder range of motion and patient reported functional outcomes following reverse total shoulder arthroplasty.

NCT ID: NCT03091075 Active, not recruiting - Rotator Cuff Tear Clinical Trials

Oxandrolone Rotator Cuff Trial

ORCT
Start date: September 23, 2018
Phase: N/A
Study type: Interventional

This study is about healing after a rotator cuff tear repair procedure. We hope to learn if a biologic medication: Oxandrolone, a synthetic derivative of the human hormone Testosterone (the principal male sex hormone and an anabolic steroid), given for 12 weeks following rotator cuff repair, is effective in aiding in the healing process and restoring muscle mass.

NCT ID: NCT03061942 Completed - Rotator Cuff Tears Clinical Trials

Arthroscopic Rotator Cuff Repair With Synovectomy

Start date: March 8, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the effect of synovectomy on clinical outcomes of arthroscopic rotator cuff repair.

NCT ID: NCT03054753 Completed - Rotator Cuff Tear Clinical Trials

Prospective Sensor Controlled Compliance Analysis of Shoulder Abduction Splint After Rotator Cuff Repair

SENSABDUKT
Start date: March 31, 2017
Phase: N/A
Study type: Interventional

The postoperative shoulder rehabilitation in an abduction brace after rotator cuff reconstruction of the shoulder is crucial for a successful healing of the reconstruction. In this study the investigators want to analyse the abduction brace-wearing time using a electronic sensor, which is implanted in the abduction brace. The participants will be informed about the sensor after completion of the abduction brace rehabilitation 6 weeks postoperatively.

NCT ID: NCT03054129 Completed - Rotator Cuff Injury Clinical Trials

Efficacy of Balance Training in Patients With Rotator Cuff Disease

Start date: June 7, 2017
Phase: N/A
Study type: Interventional

The purpose of the study is to determine whether balance training is effective in patients with rotator cuff disease.

NCT ID: NCT03018210 Recruiting - Rotator Cuff Tear Clinical Trials

The Impact of Psychological Factors on the Outcome of Surgical Repair for Rotator Cuff

IMPROVE
Start date: January 2017
Phase:
Study type: Observational

The proposed study will be a multi-centre, prospective, observational cohort to determine if psychological well-being has an impact on the outcome of surgical repair for rotator cuff tears.

NCT ID: NCT03001050 Withdrawn - Rotator Cuff Tear Clinical Trials

Rotator Cuff: Does the Vascularity Matter and the Role for PINPOINT

Start date: December 20, 2017
Phase: N/A
Study type: Interventional

The overall goal of doing this study is to improve long term patient function and outcomes in the healing rates of Rotator Cuffs. The investigators would also like to see if this method can be more cost effective and time efficient for Rotator Cuff evaluation during arthroscopy.

NCT ID: NCT02969135 Completed - Rotator Cuff Tear Clinical Trials

Progressive Active Exercise After Surgical Rotator Cuff Repair

Start date: February 26, 2017
Phase: N/A
Study type: Interventional

Shoulder disorders are extremely common, with a life-time prevalence in population of 30%. About 23% of the working population with shoulder problems are sick-listed. Specifically rotator cuff tears are considered some of the principal causes of chronic shoulder pain and disability, especially with advancing age. The National Patient Register in Denmark has registered 730 rotator cuff repairs in 2006 and 990 in 2012, which represents a 35% increase. A rotator cuff tear is defined as a rupture of the tendon (s) of the shoulder, and most frequently involves the supraspinatus and/or the infraspinatus tendon, resulting in loss of function due to pain and tissue weakness. Little is known about the effects of the postoperative training/rehabilitation, and this provides an unclear picture of the total treatment procedure of this condition. The Danish National Clinical Guidelines from 2013 recommend that these patients are offered rehabilitation and that the shoulder is immobilized post-surgery, but the evidence for postoperative training is moderate- low. The past few years, there have been conducted 5 systematic reviews looking at different rehabilitation parameters after rotator cuff surgery. They conclude that early Range-Of-Motion exercise accelerate healing, reduce stiffness, do not increase risk of re-rupture and that immobilization do not increase tendon healing or clinical outcome. They also conclude that there is a further need to evaluate approaches that foster early initiation of rehabilitation and gradual introduction of functional load in high-quality, adequately powered trials, also considering key outcomes such as return to work. Therefore, the aim of this study is to compare the effect of a progressive early passive and active movement protocol with a care as usual (limited early passive movement protocol) on tendon healing, physical function, pain, and quality of life, in patients operated due to traumatic full thickness rotator cuff tear in a Randomized Controlled Trial. Shortterm effects of physical function, pain, and quality of life will be studied as primary patient reported outcome, while secondary outcomes will be clinical and paraclinical outcomes in addition to the longterm effects of physical function, pain, and quality of life.

NCT ID: NCT02967640 Recruiting - Chronic Pain Clinical Trials

Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy?

Start date: May 1, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

The hypothesis of the present study is that in patients with rotator cuff tendinopathy a specific pharmacological blocking of peripheral glutamate-receptor N-methyl-d-aspartate receptor type1 (NMDAR) glutamate receptors will result in pain alleviation. Activated NMDAR1 has been demonstrated to be crucial for pain regulation in various pain disorders, and in biopsies from patients with tendinopathy, NMDAR1 was found to be activated. To test this hypothesis a specific NMDA receptor antagonist, ketalar (ketamine), will be injected guided by ultrasound into the subacromial space in patients with rotator cuff tendinopathy, and subsequently the pain response will be assessed.