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Rosacea clinical trials

View clinical trials related to Rosacea.

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NCT ID: NCT04025801 Not yet recruiting - Hypertension Clinical Trials

Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals

Start date: July 31, 2019
Phase:
Study type: Observational

In vivo confocal microscopy (IVCM) has been used in clinical settings for more than 25 years, and is noninvasive, rapid and easily repeatable technique to investigate ocular surface disorders. It enables morphological and quantitative analysis of ocular surface microstructure. [1-3] As the technology advances, new IVCM machine, Heidelberg Retinal Tomograph with Rostock Corneal Module (HRT-RCM), was developed. Hardware and software modifications and acquisition techniques continue to expand the applications of the HRT-RCM for quantitative in vivo corneal imaging at the cellular level. The new software can access the corneal nerve more accurate. Here the investigators proposed this Institutional Review Board (IRB) to collect healthy persons and cases of different systematic diseases as well as etiologies of ocular surface diseases.

NCT ID: NCT03989492 Recruiting - Rosacea Clinical Trials

Role of the Sympathetic Nervous System in Rosacea

Start date: May 24, 2019
Phase: N/A
Study type: Interventional

Rosacea is a common skin disorder which causes facial redness and inflammation in about 16 million Americans, from an unknown cause. Many triggers of rosacea symptoms are stressors that affect the sympathetic ("fight or flight") portion of the nervous system, and a recent pilot study suggests there is sympathetic dysfunction in rosacea. This project will benefit patients, clinicians, and basic scientists by increasing our understanding of sympathetic nervous system involvement in rosacea symptoms in order to develop improved treatments for patients with rosacea.

NCT ID: NCT03954444 Completed - Rosacea Clinical Trials

A Clinical Endpoint Bioequivalence Study of "Oxymetazoline Hydrochloride Cream"

Start date: April 15, 2019
Phase: Phase 3
Study type: Interventional

A Randomized, Double-blind, Parallel-group, Three-arm, Placebo-controlled, Multi-Site Therapeutic Equivalence Study with Clinical End-points Comparing Test Product "Oxymetazoline hydrochloride Cream, 1%" to Reference Product "RHOFADEā„¢ Cream, 1%" in the Treatment of Moderate to Severe Persistent Facial Erythema of Rosacea

NCT ID: NCT03883945 Withdrawn - Clinical trials for Papulopustular Rosacea

A Safety and Efficacy Study to Evaluate Rosacea

Start date: July 2021
Phase: Phase 1/Phase 2
Study type: Interventional

To evaluate the safety, efficacy, and pharmacokinetic profile of ascending concentrations of the study medication compared with vehicle in subjects with rosacea.

NCT ID: NCT03878784 Completed - Rosacea Clinical Trials

PACAP38 Induced Headache and Rosacea-like Symptoms in Patients With Rosacea

Start date: November 12, 2018
Phase: N/A
Study type: Interventional

The investigators aim is to investigate the incidence of headache and rosacea-like flushing after pituitary adenylate cyclase-activating peptide-38 (PACAP38) with and without treatment with sumatriptan in patients with rosacea

NCT ID: NCT03872050 Completed - Migraine Clinical Trials

Deep Phenotyping of Rosacea and Migraine

Start date: September 14, 2018
Phase:
Study type: Observational

This study aims to deep phenotype patients with rosacea and migraine

NCT ID: NCT03864978 Recruiting - Clinical trials for Papulopustular Rosacea

Safety and Efficacy of Rifaximin in Patients With Papulopustular Rosacea and Positive Lactulose Breath Test

Start date: June 22, 2018
Phase: Phase 2
Study type: Interventional

Preliminary evidence suggests that treatment with rifaximin may be beneficial in patients with papulopustular rosacea. The present clinical trial is aimed to investigate the safety and efficacy of oral rifaximin delayed release versus placebo in adults with moderate-to-severe papulopustular rosacea (a.k.a. subtype II) and positive lactulose H2/CH4 breath test.

NCT ID: NCT03841032 Completed - Rosacea Clinical Trials

4 Week In-Use Study Evaluating How Well-Tolerated a Skin Care Product Is on Adults With Facial Redness

Start date: January 28, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate if the test sunscreen skin care product will be well-tolerated and help facial redness when applied to the face after 4 weeks.

NCT ID: NCT03756389 Suspended - Rosacea Clinical Trials

Evaluation of Topical Application of BMX-010 in Subjects With Rosacea

Start date: January 3, 2018
Phase: Phase 2
Study type: Interventional

This is an exploratory Phase 2 trial of BMX-010 in patients with Rosacea which will be conducted in two parts. Up to 210 subjects with Rosacea will be enrolled.

NCT ID: NCT03708263 Terminated - Clinical trials for Erythematotelangiectatic Rosacea

Evaluation of the New Laser PHOTOLASE PLV-585nm for the Treatment of Rosacea

ROSAPHOTOLASE
Start date: September 8, 2020
Phase: N/A
Study type: Interventional

Rosacea is a frequent dermatological condition, with a chronic and disturbing evolution that is characterized by redness, permanent erythema associated with telangiectasia (visible and permanent dilatation of the small vessels). It frequently affects men and women with fair skin and can have significant psycho-emotional consequences. To counteract the unaesthetic appearance of redness and eliminate telangiectasia, the use of the laser is proposed to the patient. This study is a single center prospective, randomized, controlled split face study to compare 532nm KTP laser versus 585 nm PLV Laser in terms of improvement of the symptoms in the treatment of Erythematotelangiectatic Rosacea 20 subjects will receive up to 3 laser treatments at day 0, month 2 and 4 and will be followed at month 6 and 12.