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Rhinitis, Allergic clinical trials

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NCT ID: NCT04802616 Completed - Clinical trials for Allergic Rhinitis Due to Grass Pollen

The Influence of Nonspecific Immunostimulation on Changes in the Concentration of iNKT Cells

Start date: March 22, 2021
Phase: Phase 3
Study type: Interventional

The aim of the study is to assess the effect of polyvalent mechanical bacterial lysate (PMBL, Ismigen) on the clinical course of grass pollen-induced allergic rhinitis (using: total nasal symptom score, visual analogue scale, peak nasal inspiratory flow measurement) in children aged 5 to 17 and to assess changes in the concentration of iNKT cells under the influence of the therapy. Half of the 80 participants will receive PMBL while the other half will receive placebo.

NCT ID: NCT04729517 Completed - Clinical trials for Allergic Rhinitis Due to Allergens

Efficacy and Safety Study of AI201901 in Allergic Rhinitis Patients

HILARIA
Start date: April 20, 2021
Phase: Phase 3
Study type: Interventional

This is a prospective, national, randomized, multicenter, parallel group, Phase III study that evaluates the effects of AI201901 in Allergic Rhinitis patients, where they will spray twice a day against azelastine into both nostrils during a 28-day follow-up period.

NCT ID: NCT04709614 Completed - Clinical trials for Seasonal Allergic Rhinitis

Psychological Factors That Influence Severity of Allergic Rhinitis

Start date: January 1, 2016
Phase:
Study type: Observational

Objective biomarker of allergic rhinitis severity is necessary for monitoring disease severity and response to treatment in clinical setting and for research. We believe that psychological factors are the missing link between patient-perceived severity of allergic rhinitis and objective biomarkers. In our pilot study, several psychological factors were studied in relation to patient reported outcomes for severity of allergic rhinitis.

NCT ID: NCT04709575 Completed - Allergic Rhinitis Clinical Trials

Study to Assess the Efficacy of Anti-Bet v 1 Monoclonal Antibodies in Adults to Reduce Symptoms of Seasonal Allergic Rhinitis

Start date: January 14, 2021
Phase: Phase 3
Study type: Interventional

The primary objective is to assess the reduction of allergic symptoms as measured by combined symptom and medication score (CSMS) during birch pollen season after a single dose of REGN5713-5714-5715 versus placebo.

NCT ID: NCT04687059 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

An Exploratory Study of PQ Grass 27600 SU

Start date: October 19, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

PQGrass309 is aimed at exploring the expected average treatment effect of PQ Grass 27600 SU cumulative dose on symptom and medication score in a field setting. The study will enrol adult subjects with seasonal allergic rhinitis and/or rhinoconjunctivitis (SAR) induced by grass pollen exposure.

NCT ID: NCT04670627 Completed - Clinical trials for Seasonal Allergic Rhinitis

Biomarkers in Nasal Samples of Seasonal Allergic Rhinitics

GSK AR ELF
Start date: March 22, 2021
Phase:
Study type: Observational

The purpose of this study is to analyze nasal samples for the presence of biomarkers of allergic inflammation as well as cold and flu infections, and compare these samples both in and out of an individual's active allergy season. 40 subjects who suffer from seasonal allergies will be recruited and seen both in and out of allergy season, and 10 healthy controls. Nasal epithelial lining fluid (NELF,) collected by placing small filter papers into the nostrils, blood for analysis and a cold/flu swab will be collected at each study visit.

NCT ID: NCT04654702 Completed - Asthma Clinical Trials

Observational Study to Evaluate Therapeutic Effectiveness and Safety of Monterizine Cap.

Start date: November 17, 2017
Phase:
Study type: Observational

Investigator examines the past prescription patterns and the reasons for the change of prescription to Monterizine capsules for Perennial Allergic Rhinitis patients with Asthma who will be taking Monterizine capsules to treat allergic rhinitis. After being given Monterizine capsules, Investigator evaluates the therapeutic effectiveness and safety for 3 months (or 6 months).

NCT ID: NCT04652245 Completed - Clinical trials for Seasonal Allergic Rhinitis

Dymista Allergen Chamber - Onset of Action Study

Start date: December 14, 2020
Phase: Phase 4
Study type: Interventional

This study is to assess the onset of action of fixed drug combination of azelastine hydrochloride and fluticasone propionate nasal spray (Dymista) in treating the nasal symptoms of seasonal allergic rhinitis (SAR) induced by an allergen challenge in an Environmental Exposure Unit (EEU).

NCT ID: NCT04648930 Completed - Allergic Rhinitis Clinical Trials

Special Drug Use Observational Study of Xolair in Patients With Severe to Most Severe Seasonal Allergic Rhinitis Aged ≥ 12 Years and < 18 Years Whose Symptoms Were Inadequately Controlled Despite to Conventional Therapies

Start date: January 27, 2021
Phase:
Study type: Observational

This was a multicenter, uncontrolled, open-label, special drug use study to investigate the safety and efficacy of Xolair by collecting data in its clinical setting in patients with severe to most severe seasonal allergic rhinitis aged ≥ 12 years and < 18 years whose symptoms were inadequately controlled despite to conventional therapies and used Xolair.

NCT ID: NCT04645979 Completed - Rhinitis, Allergic Clinical Trials

A Study to Learn What Participants Think of Treatment With Betamethasone Plus Loratadine to Treat Their Acute Allergic Rhinitis, Also Known as Hay Fever in Mexico

Start date: November 11, 2020
Phase:
Study type: Observational

Acute allergic rhinitis is a common allergic reaction to things like pollen or dust. It causes inflammation inside the nose, resulting in symptoms similar to the common cold. Allergic rhinitis is also known as hay fever. In this study, the researchers want to learn what participants think of betamethasone plus loratadine as a treatment for their acute allergic rhinitis. These participants will have used betamethasone plus loratadine as a treatment for their acute allergic rhinitis within the past two months. During the study, participants will complete an online questionnaire about their experience with betamethasone plus loratadine.