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Rhinitis, Allergic clinical trials

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NCT ID: NCT00118729 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

Study In Adolescent And Adult Subjects 12 Years Of Age And Older With Seasonal Allergic Rhinitis To Assess Onset of Action

Start date: April 2005
Phase: Phase 3
Study type: Interventional

Allergic rhinitis is an inflammatory disorder of the upper airway that occurs following allergen exposure. The focus of this study, seasonal allergic rhinitis (SAR), is one type of allergic rhinitis that is triggered by the pollen from trees, grasses, and weeds. Commonly referred to as "hay fever", it is characterized by sneezing, nasal congestion and pruritus, rhinorrhea, and pruritic, watery, red eyes. The purpose of this study is to evaluate the onset of action of an investigational nasal spray, GW685698X aqueous nasal spray, versus vehicle placebo nasal spray in the treatment of seasonal allergic rhinitis caused by ragweed following a single dose of treatment in controlled pollen concentrations in an allergen challenge chamber.

NCT ID: NCT00116883 Completed - Clinical trials for Rhinitis, Allergic, Perennial

A Study Of GW685698X For The Treatment Of Perennial Allergic Rhinitis In Pediatrics

Start date: February 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the effect of an aqueous nasal spray investigational compound GW685698X compared to placebo on the hypothalamic pituitary adrenocortical (HPA) axis system in children 2 to 11 years of age with perennial allergic rhinitis.

NCT ID: NCT00116818 Completed - Clinical trials for Rhinitis, Allergic, Perennial

A Study of GW685698X for the Treatment Of Perennial Allergic Rhinitis in Adolescents and Adults

Start date: January 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the effect of an aqueous nasal spray investigational compound compared to placebo on the hypothalamic pituitary adrenocortical (HPA) axis system in adolescents and adults 12 to 65 years of age with perennial allergic rhinitis. This study can last up to 6 weeks and you will come to the clinic up to 7 times. Clinic visits include physical examinations, vital sign assessments, clinical laboratory assessments, ECGs and allergy skin testing. You will need to complete a daily diary card and spend the night in the clinic on 2 occasions to collect urine and blood samples over 24 hour periods.

NCT ID: NCT00115622 Completed - Clinical trials for Seasonal Allergic Rhinitis

Study In Adults And Adolescents With Seasonal Allergic Rhinitis

Start date: December 2004
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the efficacy and safety of an investigational nasal spray compared with placebo nasal spray in the treatment of seasonal allergic rhinitis. Allergic rhinitis is an inflammatory disorder of the upper airway that occurs following allergen exposure. The focus of this study, seasonal allergic rhinitis (SAR), is one type of allergic rhinitis that is triggered by the pollen from trees, grasses, and weeds. Commonly referred to as "hay fever", it is characterized by sneezing, nasal congestion and pruritus, rhinorrhea, and pruritic, watery, red eyes.

NCT ID: NCT00109486 Completed - Clinical trials for Rhinitis, Allergic, Perennial and Seasonal

Safety Study To Assess Growth In Children With Seasonal Allergic And/Or Perennial Allergic Rhinitis Treated With GW685698X Aqueous Nasal Spray Or Placebo Nasal Spray

Start date: April 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess any effect in children with seasonal and/or perennial allergic rhinitis by GW685698X aqueous nasal spray (versus vehicle placebo nasal spray) on growth using knemometry.

NCT ID: NCT00108914 Completed - Clinical trials for Rhinitis, Allergic, Perennial

Perennial Allergic Rhinitis Study In Pediatric Subjects

Start date: February 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the investigational drug is effective and safe in children with perennial allergic rhinitis.

NCT ID: NCT00107757 Completed - Clinical trials for Rhinitis, Allergic, Perennial

Seasonal Allergic Rhinitis In Pediatric Subjects

Start date: March 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the investigational drug is effective and safe in children with seasonal allergic rhinitis.

NCT ID: NCT00103454 Completed - Clinical trials for Rhinitis, Allergic, Perennial

A Study To Evaluate The Efficacy And Safety Of A Once-Daily Investigational Nasal Spray In Adults And Adolescents With Perennial Allergic Rhinitis (PAR).

Start date: January 2005
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to compare the efficacy and safety of GW685698X 100mcg once daily (QD) aqueous nasal spray with vehicle placebo nasal spray in adult and adolescent subjects (12 years of age and older) with perennial allergic rhinitis (PAR).

NCT ID: NCT00092885 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

An Approved Drug to Study a New Indication for Seasonal Allergic Rhinitis in Patients With Asthma (0476-269)

Start date: March 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the effect of an approved medication on the symptoms of seasonal allergic rhinitis (a seasonal variety of inflammation of the mucous membrane of the nose) in patients who are experiencing symptoms of seasonal allergic rhinitis and asthma.

NCT ID: NCT00092118 Completed - Clinical trials for Rhinitis, Allergic, Perennial

The Clinical Effects of Montelukast in Patients With Perennial Allergic Rhinitis (0476-265)

Start date: October 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine the effect of an approved medication on the symptoms of perennial allergic rhinitis (an inflammation of the mucous membrane of the nose similar to that found in hay fever except that symptoms persist throughout the year), in patients who have a history of perennial allergic rhinitis.