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Rhinitis, Allergic clinical trials

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NCT ID: NCT00789152 Completed - Allergic Rhinitis Clinical Trials

The Effect of Desloratadine and Levocetirizine on Nasal Obstruction (Study P03609)

Start date: December 1, 2003
Phase: Phase 3
Study type: Interventional

This was a study to measure the ability of desloratadine and levocetirizine to decrease nasal obstruction in subjects who had study-induced allergic rhinitis. Study participants had allergic rhinitis symptoms induced in a Vienna Challenge Chamber and then received desloratadine or levocetirizine for 8 days. After at least a 10 to 35-day washout period (time when no drug is given), subjects received the opposite treatment for 8 days. Subjects had their total nasal symptom measured.on the 8th day of each treatment period.

NCT ID: NCT00784732 Completed - Clinical trials for Seasonal Allergic Rhinitis

A Study to Compare the Efficacy of QAV680 Against Placebo in Treating Seasonal Allergic Rhinitis in an Environmental Exposure Chamber

Start date: September 2008
Phase: Phase 2
Study type: Interventional

This study will compare the effectiveness of QAV680 against placebo in treating the symptoms of seasonal allergic rhinitis in an Environmental Exposure Chamber.

NCT ID: NCT00783458 Completed - Allergic Rhinitis Clinical Trials

Single Dose Crossover Study of Patient Preference for Unscented Nasonex® Nasal Spray Versus Scented Flonase® Nasal Spray (Study P04208)

Start date: December 1, 2004
Phase: Phase 4
Study type: Interventional

This was a one-day single dose trial conducted to compare patient's preference for Nasonex® (mometasone) versus Flonase® nasal spray. Each patient was randomized to take one dose (2 sprays in each nostril) of Nasonex or Flonase. Thirty minutes later, each patient was to take one dose of the opposite medication. Questionnaires were given to each patient after each drug dose to evaluate patient product preference.

NCT ID: NCT00783237 Completed - Allergic Rhinitis Clinical Trials

Onset of Effect of Mometasone Nasal Spray in Induced Allergic Rhinitis (Study P03431)

Start date: December 1, 2003
Phase: Phase 4
Study type: Interventional

This was a single-dose study to determine the time it takes for mometasone furoate nasal spray to go in effect, after a single dose of 2 sprays per nostril. Patients who are eligible were exposed to ragweed pollen for 3 hours on one or two occasions. Patients who experienced adequate symptoms during the pollen exposure phase came back for a Treatment Phase visit. During the Treatment Phase visit, patients were exposed to ragweed pollen for 2 hours and then received either mometasone or placebo nasal spray. Symptom evaluations began on the patients every hour for the next 11 hours.

NCT ID: NCT00783224 Completed - Clinical trials for Perennial Allergic Rhinitis

A Comparative Study of Mometasone Furoate Nasal Spray and Fluticasone Propionate Nasal Spray in Patients With Perennial Allergic Rhinitis (Study P04512)

Start date: September 2005
Phase: Phase 3
Study type: Interventional

This study was conducted to see if mometasone nasal spray is efficaceous for the treatment of perennial allergic rhinitis. Patients will be randomized to active mometasone, placebo mometasone, active fluticasone, or placebo fluticasone.

NCT ID: NCT00783211 Completed - Clinical trials for Seasonal Allergic Rhinitis

Efficacy and Safety of Desloratadine vs. Fexofenadine 180 mg. vs. Placebo for Treating Seasonal Allergic Rhinitis (SAR)(Study P04053)(COMPLETED)

Start date: August 1, 2004
Phase: Phase 4
Study type: Interventional

This was a randomized, double-blind, parallel-group, multicenter study that used both an active control (fexofenadine) and a placebo control to evaluate desloratadine 5 mg once daily during a 15-day treatment period. The active treatments and placebo were allocated in a 2:2:1 ratio.

NCT ID: NCT00783198 Completed - Conjunctivitis Clinical Trials

Efficacy and Long-Term Safety of Ragweed (Ambrosia Artemisiifolia) Sublingual Tablet in Adults With a History of Ragweed-Induced Rhinoconjunctivitis With or Without Asthma (Study P05233)(COMPLETED)

Start date: September 2009
Phase: Phase 2/Phase 3
Study type: Interventional

This study will evaluate the efficacy and safety of ragweed sublingual tablet (SCH 39641/MK-3641) compared with placebo in participants with ragweed-induced rhinoconjunctivitis over a one-year period. It is expected that ragweed allergic participants on one of the active arms of the trial will have decreased allergic rhinoconjunctivitis symptoms and require less allergy rescue medications during ragweed pollen season.

NCT ID: NCT00783146 Completed - Clinical trials for Seasonal Allergic Rhinitis

Efficacy and Safety of Desloratadine vs. Fexofenadine 180 mg. vs. Placebo for Treating Seasonal Allergic Rhinitis (SAR) (Study P04054)

Start date: August 1, 2004
Phase: Phase 4
Study type: Interventional

This was a randomized, double-blind, parallel-group, multicenter study that used both an active control (fexofenadine) and a placebo control to evaluate desloratadine 5 mg once daily during a 15-day treatment period. The active treatments and placebo were allocated in a 2:2:1 ratio.

NCT ID: NCT00783133 Completed - Clinical trials for Seasonal Allergic Rhinitis

Preference for Clarinex Tablets vs. Allegra Tablets in Patients With Seasonal Allergies (Study P03177)

Start date: November 1, 2002
Phase: Phase 4
Study type: Interventional

This was a crossover study designed to see if patients with seasonal allergy symptoms preferred Clarinex® or Allegra®. Patients were randomized to take 7 days of Clarinex or Allegra treatment, followed by a 5 to 28-day washout period (days when no drug is given), followed by 7 days of the opposite treatment. At the end of each 7-day treatment, patients were asked questions to determine which drug, Clarinex or Allegra, the patient prefers more.

NCT ID: NCT00779740 Completed - Clinical trials for Rhinitis, Allergic, Perennial

Equivalency Study of Two Formulations of Mometasone Furoate Nasal Spray (Study P04419)

Start date: February 1, 2005
Phase: Phase 3
Study type: Interventional

This is a multicenter, open-label, randomized, parallel group comparison study to verify the clinical equivalency of the old formulation (50 mcg as mometasone furoate [MF] in 50 μL of solution per spray) to the new formulation (50 mcg as MF in 100 μL of solution per spray) in patients with perennial allergic rhinitis.