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Rhinitis, Allergic clinical trials

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NCT ID: NCT01030146 Completed - Rhinitis Clinical Trials

Management of Allergic Rhinitis Patients With Nasal Steroids and NeilMed® Sinus Rinseā„¢ System With Isotonic Saline

Start date: December 2009
Phase: N/A
Study type: Interventional

You are being asked to volunteer for a research study. You are being asked to participate in this study because you have completed at least one month of drug treatment with a nasal steroid and allergy testing and still have symptoms. This research study is sponsored by NeilMed Pharmaceuticals, Inc. The purpose of this study is to compare quality of life outcomes in patients who continue medical treatment plus the use of the NeilMed Sinus Rinse low-pressure pump with saline. Your participation in this study may help to improve the management of patients with allergic rhinitis. Allergic rhinitis is a common health problem, affecting between 10% and 40% of the world's population. Presently, antihistamines and nasal steroids are the standard treatment for allergic rhinitis. To further clarify these findings, we propose a study comparing the differences in quality of life improvements, by using a series of questionnaires, between subjects electing continued medical management and those electing medical treatment plus nasal wash. The investigators in charge of the study are Dr. Rodney J. Schlosser and Dr. Shaun A. Nguyen. Approximately 40 patients will be enrolled in this study at the Medical University of South Carolina (MUSC Hospital). You will have the choice of choosing either to receive only medical treatment or to receive medical treatment with nasal wash.

NCT ID: NCT01024608 Completed - Clinical trials for Seasonal Allergic Rhinitis

Study in Adult and Adolescent Subjects With Seasonal Allergic Rhinitis (SAR)

Start date: December 31, 2009
Phase: Phase 3
Study type: Interventional

The purpose of the study is to assess the efficacy and safety of an investigational nasal aerosol compared with placebo nasal aerosol in the treatment of seasonal allergic rhinitis.

NCT ID: NCT01018693 Completed - Clinical trials for Seasonal Allergic Rhinitis

A Study to Determine the Capacity of VAK694 When Combined With Allergen Immunotherapy to Bring About Specific Immune Tolerance

Start date: November 2009
Phase: Phase 2
Study type: Interventional

The purpose of the study is to determine whether VAK694 when combined with subcutaneous immunotherapy leads to long term immune tolerance to allergen in individuals with seasonal allergic rhinitis.

NCT ID: NCT00997620 Completed - Clinical trials for Seasonal Allergic Rhinitis

Fluticasone Furoate Treatment of Daytime Somnolence and Cognitive Performance in Seasonal Allergic Rhinitis

Start date: March 2010
Phase: Phase 4
Study type: Interventional

The hypothesis is that treating hay fever patients who had daytime sleepiness and slowed thinking because of the hay fever will improve when treated with an effective anti-hay fever medication, an intranasal steroid, that is will have less daytime sleepiness and demonstrate better thinking.

NCT ID: NCT00988247 Completed - Clinical trials for Rhinitis, Allergic, Perennial

Long Term Safety and Efficacy Trial of Beclomethasone Dipropionate - Hydrofluoroalkane (BDP-HFA) 320 mcg in Allergic Rhinitis

Start date: October 31, 2009
Phase: Phase 3
Study type: Interventional

Subjects with perennial allergic rhinitis will be randomized to 320 mcg of beclomethasone dipropionate (BDP) using a hydrofluoroalkane (HFA) propellant or placebo as a nasal aerosol. The subjects will be followed for safety and efficacy for a period of 30 or 52 weeks. BDP HFA is a steroid which is currently FDA approved for the treatment of asthma. BDP-HFA should be safe and effective as a "dry" nasal aerosol which may be preferred by some patients.

NCT ID: NCT00979901 Completed - Clinical trials for Seasonal Allergic Rhinitis

Montelukast in Patients With Seasonal Allergic Rhinitis - Spring 2000 Study (MK-0476A-162)(COMPLETED)

Start date: March 2000
Phase: Phase 3
Study type: Interventional

This study will evaluate the ability of montelukast to improve the signs and symptoms of seasonal allergic rhinitis compared with loratadine and placebo.

NCT ID: NCT00974571 Completed - Clinical trials for Perennial Allergic Rhinitis

Montelukast in Perennial Allergic Rhinitis - 2001-2002 Study (0476-246)

Start date: November 2001
Phase: Phase 3
Study type: Interventional

This study will assess the ability of montelukast to improve the signs and symptoms of perennial allergic rhinitis compared to placebo. Cetirizine is included in the study as an active control.

NCT ID: NCT00972738 Completed - Clinical trials for Seasonal Allergic Rhinitis

Montelukast in Seasonal Allergic Rhinitis - Spring 2001 Study (0476-235)

Start date: April 2001
Phase: Phase 3
Study type: Interventional

This study will assess the treatment effect of montelukast versus placebo over a 2 week period in patients with seasonal allergic rhinitis. Loratadine is included in the study as an active comparator.

NCT ID: NCT00972504 Completed - Clinical trials for Rhinitis, Allergic, Seasonal

723/726 Proof of Concept Study in Allergen Challenge Chamber in Hannover

Start date: June 2009
Phase: Phase 2
Study type: Interventional

This is a randomised, double-blind, placebo-controlled 4-period cross-over study to assess the efficacy and safety of repeat dose intranasal GSK1004723 (1000µg), oral GSK835726 (10mg) and cetirizine (10mg) in the environmental challenge chamber in subjects with seasonal allergic rhinitis.

NCT ID: NCT00968149 Completed - Clinical trials for Seasonal Allergic Rhinitis

A Study Comparing Montelukast With Placebo in Children With Seasonal Allergic Rhinitis (0476-219)(COMPLETED)

Start date: March 2001
Phase: Phase 3
Study type: Interventional

This study will evaluate the effect of montelukast compared to placebo in children during the spring allergic rhinitis season.