Yoga for Rheumatoid Arthritis

Rheumatoid Arthritis Clinical Trial

Official title:

Yoga for Persons With Rheumatoid Arthritis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00349869
• Other study ID #: F31AT003362-01A1
• Secondary ID: F31AT003362-01A1
• Status: Completed
• Phase: N/A
• Start date: August 2006
• Est. completion date: August 2011

Study information

• Verified date: June 2023
• Source: Johns Hopkins University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the impact of yoga on inflammatory arthritis and knee osteoarthritis.

Description:

Yoga is a set of ancient Indian theories and practices, focusing on unifying mind, body, and spirit, and promoting strength, balance, and flexibility. The physical aspect of yoga includes poses, breathing techniques, and relaxation. Inflammatory arthritis, a chronic disease characterized by inflammation of the lining of the joints, can cause long-term joint damage, resulting in chronic pain, loss of function, and disability. The primary objective of this study is to learn how people with inflammatory arthritis and knee osteoarthritis respond to an exercise program of yoga. To accomplish this, 30 persons with inflammatory arthritis or knee osteoarthritis will be randomly assigned to one of two groups. Group one will begin an immediate 8-week program of yoga classes consisting of 60-minute sessions, twice a week. Group two, or the "waitlist" control group, will receive 8 weeks of arthritis education followed by the same 8-week yoga program as group one. Participants also will have blood drawn, and complete various tests. The yoga classes will be taught by an experienced, certified yoga instructor, and are designed especially for the needs of people with inflammatory arthritis and knee osteoarthritis. This study will provide important data on integrating mind-body activities into the treatment of inflammatory arthritis and knee osteoarthritis.

Other known NCT identifiers

• NCT00346307

Recruitment information / eligibility

• Status: Completed
• Enrollment: 75
• Est. completion date: August 2011
• Est. primary completion date: August 2010
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age 18+ (RA only upper age limit 70)
• Confirmed or probable OA (using pre-specified criteria) OR Rheumatoid arthritis (participation approved by rheumatologist)
• Currently sedentary (physically active for 20 min < 3times/week)

Exclusion Criteria:

• Inability to ambulate without use of assistive device
• Uncontrolled high blood pressure or existing heart condition
• Co-morbid inflammatory condition with overlapping symptoms (i.e., fibromyalgia)
• Surgery within 6 months

Related Conditions & MeSH terms

• Arthritis
• Arthritis, Rheumatoid
• Osteoarthritis
• Rheumatoid Arthritis

Intervention

Behavioral:
• yoga
8-week yoga program.

Locations

Country	Name	City	State
United States	Johns Hopkins Arthritis Center, 5501 Hopkins-Bayview Circle, Ste 1B.14	Baltimore	Maryland

Sponsors (2)

Lead Sponsor	Collaborator
Johns Hopkins University	National Center for Complementary and Integrative Health (NCCIH)

Country where clinical trial is conducted

United States, 

References & Publications (5)

Bartlett SJ, Moonaz SH, Mill C, Bernatsky S, Bingham CO 3rd. Yoga in rheumatic diseases. Curr Rheumatol Rep. 2013 Dec;15(12):387. doi: 10.1007/s11926-013-0387-2. — View Citation

Haaz S, Bartlett SJ. Yoga for arthritis: a scoping review. Rheum Dis Clin North Am. 2011 Feb;37(1):33-46. doi: 10.1016/j.rdc.2010.11.001. Epub 2010 Dec 3. — View Citation

Haaz S, Bingham CO, Bathon JM, Bartlett SJ. The effect of yoga on clinical parameters in patients with rheumatoid arthritis. Arthritis & Rheumatism 2008;58:S893-S4.

Haaz S, Bingham III CO, Bartlett SJ. Adherence to an 8-week yoga program for RA and OA: Who drops out and why? Arthritis & Rheumatism 2009;60:1978.

Moonaz SH, Bingham CO 3rd, Wissow L, Bartlett SJ. Yoga in Sedentary Adults with Arthritis: Effects of a Randomized Controlled Pragmatic Trial. J Rheumatol. 2015 Jul;42(7):1194-202. doi: 10.3899/jrheum.141129. Epub 2015 Apr 1. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Physical Health	Assessed using SF36 Physical Component Score	baseline, post intervention, follow-up
Secondary	Mobility/Fitness	Change in flexibility, balance, strength, walk time	baseline, posttest, follow-up
Secondary	RA Disease Activity	DAS28 CRP score	baseline, post intervention, follow-up
Secondary	Psychological Function	Change in SF36 MCS, CES-D, PANAS, Perceived Stress and Arthritis Self Efficacy	baseline, , posttest, follow-up
Secondary	HRQL	Change in SF36 domains	baseline, post intervention, follow-up

External Links

•   Yoga for Arthritis