Clinical Audit on the Managment in Assiut University Children Hospital

Rheumatic Fever Clinical Trial

Official title:

Clinical Audit on the Managment of Rheumatic Fever in Assiut University Children Hospital

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03281863
• Other study ID #: AssiutU71516
• Status: Completed
• Start date: October 1, 2018
• Est. completion date: March 24, 2020

Study information

• Verified date: March 2021
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

clinical audit on the Managment of rheumatic fever in assiut university children hospital.

Description:

Acute rheumatic fever,an auto immune response to Group A streptococcus infection of the upper respiratory tract,may result in carditis.when the inflammation leads to permenant damage of the valves the individual has rheumatic heart disease.

Recurrences of rheumatic fever are likely in the absence of preventive measures and may cause further cardiac valve and muscle damage,leading to heart failure,stroke and premature death.bacterial endocarditis is also a complication.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: March 24, 2020
• Est. primary completion date: March 24, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: 5 Years to 15 Years

Eligibility

Inclusion Criteria:

• patients with confirmed diagnosis of rheumatic fever based on laboratory investigations.

Exclusion Criteria:

• No

Related Conditions & MeSH terms

• Fever
• Rheumatic Diseases
• Rheumatic Fever

Intervention

Diagnostic Test:
• C reactive protein, anti streptolysin o antibody test ,erythrocyte sedimentation rate
Throat culture to detect the causative organism

Locations

Country	Name	City	State
Egypt	Egypt	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	laboratory investigations (ASOt , ESR . CRP)	laboratory investigations that measure the inflammation process will be used and the target that the ASOt not increase 1/400	One year from October 2017 to september 2018
Secondary	clinical measures	improvement of arthritis if found	One year from October 2017 to september 2018