Clinical Trials Logo

Restenosis clinical trials

View clinical trials related to Restenosis.

Filter by:

NCT ID: NCT05451368 Recruiting - Clinical trials for Coronary Artery Calcification

Neointimal Features in Patients With Restenosis of Calcified Lesions

Start date: March 17, 2022
Phase:
Study type: Observational

Previous studies have suggested that restenosis (RS) after stenting is mainly due to smooth muscle cell proliferation and migration, but recent evidence suggests that in-stent restenosis(ISR) is associated with a number of factors. Coronary artery calcification is an independent predictor of ischaemia-mediated revascularisation 1 year after percutaneous coronary intervention (PCI) following RS.The characteristics of new neointima in patients with in-stent restenosis of calcified lesions are important issues to explore

NCT ID: NCT04514406 Terminated - Stenosis Clinical Trials

APERTO CVS PMCF Study

APERTO CVS
Start date: January 25, 2021
Phase:
Study type: Observational

Prospective Observational Single Arm study aimed to assess safety and effectiveness of APERTO OTW DCB in treating stenosis and restenosis of central veins in dialysis patients

NCT ID: NCT03858764 Withdrawn - Clinical trials for Peripheral Arterial Disease

Local Paclitaxel Delivery to Prevent Restenosis in Peripheral Arterial Disease

ResTAP
Start date: August 2013
Phase:
Study type: Observational

The purpose of this study is to determine if the addition of a catheter-based local delivery of paclitaxel into the peripheral arterial vessels in patients with peripheral arterial disease (PAD) and subsequent restenosis of the femoropopliteal region would benefit from this type of investigational intervention with a known antiproliferative agent.

NCT ID: NCT03613337 Recruiting - Clinical trials for Coronary Heart Disease

Effect of Smoking Status and Genetic Risk Factors on Restenosis and Efficacy of Clopidogrel After de Novo Percutaneous Coronary Intervention

Start date: May 1, 2018
Phase:
Study type: Observational

Restenosis occurs for many different reasons. Over the years, many predictive clinical, biological, genetic, epigenetic, lesion-related, and procedural risk factors for restenosis have been identified. Smoking is one of most important factors, however the results were contradictory. And the genetic factors of restenosis have been studied mostly in European populations. Based on literature review, study of candidate genes for restenosis in Chinese population was insufficient. With due attention to this matter mentioned above, the investigators aim to preliminary explore genetic variation and smoking effect on clinical restenosis in patients diagnosed with after percutaneous coronary intervention in the Chinese population, with correlation analysis of factors and gene-set analysis of biological pathways related to restenosis and platelet approach were widely used in this study.

NCT ID: NCT03332264 Completed - Stenosis Clinical Trials

Sequent Please Drug Coated Balloons Versus Primary Stent Application in Long SFA Lesions

SPORTS
Start date: March 30, 2017
Phase: N/A
Study type: Interventional

Patients with peripheral artery disease will be treated with either drug coated balloon catheter, drug coated stent or uncoated stent.

NCT ID: NCT03149913 Recruiting - Stenosis Clinical Trials

Local Paclitaxel or Balloon Angioplasty Below the Knee

SAMBA
Start date: December 15, 2016
Phase: N/A
Study type: Interventional

Patients with claudication or critical limb ischemia will be treated either with uncoated balloons or paclitaxel coated balloons in order to enhance the vessel patency in stenosed or occluded below the knee arteries

NCT ID: NCT03146221 Withdrawn - Restenosis Clinical Trials

Search for Restenosis Markers in Lower Limb Arteritis

FEMIA
Start date: June 20, 2017
Phase: N/A
Study type: Interventional

The initial hypothesis of this work is that the genesis and the evolution of the atheromatous plaque are partly controlled at the molecular level and in particular by the microRNAs through their role as regulator of the genes. The study of the tissue and serum profile over time of specific microRNAs involved in the regulation of atheromatous plaque correlated with clinical data and restenosis imaging will allow to define biological markers of restenosis in the patient with an arteritis of the lower limbs . This study is a pioneer in the field and it would be imprudent to conclude that a biomarker would be used clinically at the end of this work alone. Nevertheless this study will make a major advance in this topic, in vivo intervention studies with inhibition or over-expression of microRNA will obviously be necessary to confirm the use of these as biomarkers of arteritis of the lower limbs. Regular assay of reliable biomarkers in arterial patients will ultimately suggest early management to best adapt surgical and medical treatment.

NCT ID: NCT03141580 Completed - Clinical trials for Carotid Atherosclerosis

Long-term Follow-up NIRS-IVUS Imaging of Pre-existing Carotid Stents

Start date: July 15, 2017
Phase: N/A
Study type: Interventional

The 'Long-term Follow-up Near-infrared Spectroscopy and Intravascular Ultrasound Imaging of Internal Carotid Artery Stenosis Treated With Stenting' trial is an academic research project. It follows already published results of a research on carotid plaque composition in patients undergoing carotid stenting. Patients who were treated with carotid stenting will be invited to participate on the trial. The written informed consent will be needed. The participants will undergo carotid angiography, intravascular near-infrared spectroscopy and intravascular ultrasound of the extracranial portion of the internal and common carotid artery with implanted stent. The aim of the trial is to describe long-term change of the luminal and stent dimensions, vessel wall remodeling and plaque composition after carotid stenting. The findings will help to understand the long-term effect of carotid stenting on the carotid stenosis and mechanisms of plaque stabilization - sealing with stent.

NCT ID: NCT02790606 Completed - Stenosis Clinical Trials

Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft in AV Graft Patients (AVeVA)

AVeVA
Start date: July 2016
Phase: N/A
Study type: Interventional

The objective of this study is to assess the safety and effectiveness of the COVERA™ Vascular Covered Stent for the treatment of stenotic lesions in the upper extremity venous outflow of the Arteriovenous (AV) access circuit.

NCT ID: NCT02649946 Completed - Stenosis Clinical Trials

Clinical Study of the BARD® COVERA™ Arteriovenous (AV) Stent Graft

AVeNEW
Start date: June 2016
Phase: N/A
Study type: Interventional

The objective of this study is to assess the safety and effectiveness of the COVERA™ Vascular Covered Stent for the treatment of stenotic lesions in the upper extremity venous outflow of the Arteriovenous (AV) access circuit.