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Respiratory Tract Infections clinical trials

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NCT ID: NCT05499780 Terminated - Healthy Volunteers Clinical Trials

Study on Performance and Safety of Sentinox in the Prevention of Acute Respiratory Infections (ARI)

Start date: November 7, 2022
Phase: N/A
Study type: Interventional

This is a post market, single-center, randomized, controlled, clinical study to assessTo evaluate the performance of self-administered Sentinox intranasal spray in preventing ARI caused by at least one respiratory virus

NCT ID: NCT05279534 Terminated - Tonsillitis Clinical Trials

Efficacy and Safety of L. Plantarum and P. Acidilactici in Children With Upper Respiratory Tract Infections

Start date: March 8, 2022
Phase: N/A
Study type: Interventional

Randomized, placebo-controlled trial to evaluate the coadjuvant effect of a combination of L. plantarum and P. acidilactici probiotic strains, taken twice daily, in children 6 months to 5 years-old with upper respiratory tract infections with pharyngitis and/or tonsillitis. Main objective is to evaluate efficacy of this probiotic in reducing fever and pain, as well to evaluate its safety.

NCT ID: NCT05014516 Terminated - Clinical trials for COVID-19 Respiratory Infection

Lung Structure-Function In SurVivors of Mild and SEvere COVID-19 Infection: 129Xe MRI

LivCovidFree
Start date: August 5, 2021
Phase:
Study type: Observational

In this study the Investigators aim to deploy UTE and HP 129Xe MRI for structural and functional evaluation of persistent lung abnormalities in COVID-19 survivors.

NCT ID: NCT04912180 Terminated - Influenza Clinical Trials

Apple Respiratory Study

ARS
Start date: April 6, 2021
Phase:
Study type: Observational

The Apple Respiratory Study, a collaboration between researchers at Apple Inc. (the "Study Sponsor" or "Sponsor") and the Seattle Flu Study team at the University of Washington (UW) (the "UW Study Team"), is a prospective, longitudinal cohort, low risk Study to collect certain data from Apple Watch and iPhone to determine whether such data can detect physiologic and non-physiologic changes in individuals associated with respiratory illnesses due to influenza, SARS-CoV-2 and other respiratory pathogens (the "Study").

NCT ID: NCT04815018 Terminated - Clinical trials for SARS-CoV-2 Infection

Shifts in the Respiratory Microbiome and Clinical Outcomes of SARS-CoV-2

COVID-19
Start date: October 7, 2020
Phase:
Study type: Observational

This is a longitudinal, prospective observational study focusing on health-related outcomes relative to potential changes in the respiratory microbiome seen with weekly SARS-CoV-2 testing in nursing home residents.

NCT ID: NCT04616586 Terminated - Pneumonia Clinical Trials

SILtuximab in Viral ARds (SILVAR) Study

SILVAR
Start date: November 13, 2020
Phase: Phase 3
Study type: Interventional

This study will evaluate the efficacy and safety of siltuximab compared with normal saline in combination with standard of care (SOC) in selected hospitalized patients with COVID-19 previously treated with corticosteroids or another respiratory virus infection associated with acute respiratory distress syndrome (ARDS) and elevated C-reactive protein (CRP) levels.

NCT ID: NCT04583280 Terminated - Clinical trials for Respiratory Tract Infections

A Study of Rilematovir in Infants and Children and Subsequently in Neonates Hospitalized With Acute Respiratory Tract Infection Due to Respiratory Syncytial Virus (RSV)

DAISY
Start date: September 6, 2021
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate the efficacy of rilematovir compared to placebo treatment with respect to the clinical outcome on the RSV Recovery Scale (RRS).

NCT ID: NCT04547556 Terminated - Clinical trials for Respiratory Tract Infections

ADEQUATE Advanced Diagnostics for Enhanced QUality of Antibiotic Prescription in Respiratory Tract Infections in Emergency Rooms

ADEQUATE
Start date: October 25, 2021
Phase: N/A
Study type: Interventional

To assess the impact of rapid diagnostic testing of patients with Acute Respiratory Tract Infection (ARTI) at the emergency department, on (1) hospital admission rates and (2) antimicrobial prescriptions (days of treatment) and (3) the non-inferiority in terms of clinical outcome. Geographical and seasonal variation will be assessed on a real time basis including pathogens of public health interest. The impact will be stratified within age groups and risk factors in order to determine the long-term clinical, public health and economic determinants for the integration of diagnostics in a global and sustainable perspective.

NCT ID: NCT04505098 Terminated - Clinical trials for Cardiovascular Diseases

A Pragmatic Randomized Trial of Icosapent Ethyl for High-Cardiovascular Risk Adults

MITIGATE
Start date: August 7, 2020
Phase: Phase 4
Study type: Interventional

MITIGATE is a prospective, open-label, parallel-group, randomized, pragmatic clinical trial. The MITIGATE Study has been designed to evaluate the real-world clinical effectiveness of pre-treatment with icosapent ethyl (IPE), also known as Vascepa®, compared to usual standard of care to prevent and reduce the sequelae of laboratory-confirmed viral upper respiratory infection (URI)-related (i.e., COVID-19, influenza, and other known viral respiratory pathogens) morbidity and mortality in a high-risk cohort of adults with established atherosclerotic cardiovascular disease (ASCVD).

NCT ID: NCT04495738 Terminated - Clinical trials for Respiratory Infections in Children

Infant Formula and Toddler Drink Feeding Intervention

Start date: August 10, 2020
Phase: N/A
Study type: Interventional

The purpose of this randomized, multi-center, controlled, double-blind, parallel study is to evaluate the health and developmental outcomes of children fed a new infant formula and toddler drink through 24 months of age.