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Respiratory Sounds clinical trials

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NCT ID: NCT01734811 Completed - Clinical trials for Bronchospasm; Bronchitis

Efficacy and Safety Evaluation in Recurrent Wheezing Attacks

MV130
Start date: October 2012
Phase: Phase 3
Study type: Interventional

The study will be conducted in two hospitals of the same geographic area. It will be included children <3-years-old with recurrent wheezing attacks, confirmed by the review of the medical records, in the previous 12 months or a shorter time for those younger than one year.

NCT ID: NCT01601847 Completed - Allergy Clinical Trials

Wheezing in Black Preterm Infants: Impact of Vitamin D Supplementation Strategy

D-Wheeze
Start date: January 2013
Phase: Phase 4
Study type: Interventional

The goal of this study is to identify a vitamin D supplementation strategy that best promotes the lung, immune, and overall health of black infants born preterm (28-36 weeks gestational age). This is a high risk population that seems to have unique vitamin D needs, and inappropriate supplementation may promote wheezing or allergy. The results of this study will help form nutritional recommendations for the approximately 100,000 black infants born at 30-36 weeks gestational age in the U.S. every year.

NCT ID: NCT01265342 Completed - Clinical trials for Respiratory Tract Infections

Efficacy of Nebulised Beclometasone in Viral Wheezing Prophylaxis

ENBe
Start date: October 2010
Phase: Phase 4
Study type: Interventional

Inhaled steroids, in particular beclomethasone, are widely prescribed in Italy as symptomatic treatment of upper respiratory infections without evidence of efficacy. The purpose of this study is to evaluate the efficacy of beclomethasone (administered by nebuliser twice a day) in preventing viral wheezing in pre-school children who had had episodes in the preceding 12 months.

NCT ID: NCT01028560 Completed - Asthma Clinical Trials

Allergy Immunotherapy for the Reduction of Asthma

AIR
Start date: October 2008
Phase: Phase 1/Phase 2
Study type: Interventional

In this clinical study we aim to determine the effect of allergy immunotherapy in decreasing asthma and allergy related disease in children who had multiple episodes of wheezing and who are at high risk for developing persisting asthma. These risks include a history of asthma in the parents, allergies to environmental allergens (such as dust mite, cockroach or mouse) and other allergic diseases such as eczema or food allergies. Allergy Immunotherapy is not new and has been practiced for many years to treat asthma and environmental allergies in older children and adults, but has not yet been systematically studied in young children.

NCT ID: NCT00711399 Completed - Respiratory Sounds Clinical Trials

Assessment of Cough and Wheeze With Breath Sound Documenting Device

Start date: September 2008
Phase: N/A
Study type: Observational

The study goal is to create a database of respiratory sounds recordings, to evaluate and validate the WIM technology and to evaluate the efficacy of a specific treatment by comparing the severity of the respiratory symptoms before and after the administration of the treatment.

NCT ID: NCT00675584 Completed - Asthma Clinical Trials

CARE Network Maintenance Versus Intermittent Inhaled Steroids in Wheezing Toddlers (MIST)

MIST
Start date: August 2008
Phase: Phase 3
Study type: Interventional

Asthma affects about 4 million children in the United States and is a leading cause of hospitalizations and school absenteeism. Continuous wheezing in very young children may develop into asthma. Low doses of inhaled corticosteroids (ICS) are commonly prescribed to treat children with particularly bad wheezing episodes. This study will compare the safety and effectiveness of low doses of ICS taken daily versus higher doses of ICS taken only during respiratory tract illnesses for toddlers with continuous wheezing or coughing illnesses.

NCT ID: NCT00438646 Completed - Asthma Clinical Trials

Oral Bacteria and Allergic Disease in Children

Start date: February 2007
Phase: N/A
Study type: Observational

This study will see if bacteria differ between children who have allergies or asthma and children who do not have allergies or asthma. Previous research suggests that some bacteria may protect against allergies and asthma. This study may provide more information on why some children develop allergies and asthma. Patients at the University of North Carolina-Chapel Hill School of Dentistry who are between 6 and 11 years of age may be eligible for this study. Parents of participating children complete a questionnaire about the child and the child's health. The child provides a saliva sample by chewing a small piece of wax and spitting in a cup. The saliva sample is analyzed in the laboratory for bacteria, yeast and antibodies (substances the body produces to fight germs).

NCT ID: NCT00301171 Completed - Asthma Clinical Trials

Treatment of Persistent Wheezing in Infants and Children

Start date: September 2003
Phase: N/A
Study type: Interventional

Wheezing is a high-pitched whistling sound that is produced when air flows through narrowed lung airways. It is a common symptom of asthma. Persistent wheezing is commonly treated with bronchodilators and inhaled steroids; however, when wheezing is temporarily caused by a virus or exposure to tobacco smoke, this may not be the most effective treatment. The purpose of this study is to evaluate the cause of wheezing in infants and children and to assess the effectiveness of inhaled steroids on improving lung function.

NCT ID: NCT00189436 Completed - Asthma Clinical Trials

Effect of Nebulized Budesonide and Oral Corticosteroids on Wheezing Episode Relapse in Children

BudER
Start date: March 2003
Phase: Phase 4
Study type: Interventional

Subjects aged 1-8 years who have been discharged from the emergency department/outpatient care facility with a diagnosis of asthma/bronchospasm/wheezing after usual standard care will be enrolled into this open-label, randomized, parallel-group study to compare the efficacy of nebulized budesonide and oral corticosteroids in preventing asthma exacerbation relapse rates during the 21-day follow-up period.

NCT ID: NCT00144846 Completed - Asthma Clinical Trials

Inhaled Albuterol Sulfate For Acute Wheezing Due To Obstructive Airways Disease In Children

Start date: September 2004
Phase: Phase 3
Study type: Interventional

This study evaluates the effect of cumulative dose administration of albuterol sulfate inhalation aerosol delivered with valved holding chamber and facemask. This is a four week study in birth to 23 month old subjects who are experiencing acute wheezing due to obstructive airways disease.