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Clinical Trial Summary

This is a multicentre prospective cohort trial in adult and pediatric ICU patients. The investigators will measure the effect of a patient's inspiratory effort during mechanical ventilation on the lungs and diaphragm. The investigators will daily (for a maximum of 8 days) measure esophageal pressures with a balloon catheter to quantify inspiratory effort and respiratory muscle function, and perform daily ultrasound measurements of the diaphragm and the lungs. The investigators hypothesize that a small inspiratory effort will result in the preservation of diaphragm function and have no adverse effect on lung function.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05459116
Study type Interventional
Source University Hospital, Antwerp
Contact Vertongen
Phone +323 821 44 04
Email icu-research@uza.be
Status Recruiting
Phase N/A
Start date September 21, 2022
Completion date August 1, 2024

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