Respiratory Insufficiency Clinical Trial
Official title:
A Randomised, Feasibility Trial of Simultaneous Application of Flow at Extubation (SAFEx) in Patients Requiring Intubation and Ventilation for the Management of Acute Respiratory Failure
The goal of this feasibility study is to learn whether a new approach to breathing tube removal within the Intensive Care Unit is safe and acceptable to participants who require a breathing tube for the management of severe breathing difficulties. The main questions it aims to answer are: - What is the recruitment rate to the study over 12 months? - Is the study design acceptable and safe to participants? Participants will receive high flow nasal oxygen before their breathing tube is removed. The investigators will compare this with standard practice of applying conventional, low-flow oxygen after the breathing tube removed to see if this effects the rate of repeat breathing tube insertion. The investigators hypothesise that they will recruit 30 participants to the study protocol (15 participants in each group) over 12 months and that our study protocol will be tolerable and acceptable to participants.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT04030208 -
Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation
|
N/A | |
| Recruiting |
NCT03697785 -
Weaning Algorithm for Mechanical VEntilation
|
N/A | |
| Recruiting |
NCT02989051 -
Fluid Restriction Keeps Children Dry
|
Phase 2/Phase 3 | |
| Completed |
NCT02930525 -
Effect of High Flow Nasal Cannula vs. Standard Care on Respiratory Stability in Pediatric Procedural Sedation
|
N/A | |
| Recruiting |
NCT02539732 -
Prediction of Outcome of Weaning From Mechanical Ventilation Using the Electrical Activity of the Diaphragm
|
||
| Enrolling by invitation |
NCT02290236 -
Monitored Saturation Post-ICU
|
N/A | |
| Completed |
NCT02056119 -
RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Unit
|
N/A | |
| Terminated |
NCT01583088 -
Early Stage Amyotrophic Lateral Sclerosis Phrenic Stimulation
|
Phase 3 | |
| Withdrawn |
NCT00990119 -
High Flow Therapy (HFT) to Treat Respiratory Insufficiency in Chronic Obstructive Pulmonary Disease (COPD)
|
N/A | |
| Completed |
NCT00741949 -
Broncho-alveolar Lavage Under Noninvasive Ventilation With Propofol TCI in Patient With AHRF
|
Phase 3 | |
| Completed |
NCT01411722 -
Electrical Activity of the Diaphragm During the Weaning Period
|
Phase 2 | |
| Recruiting |
NCT00339053 -
Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair
|
Phase 4 | |
| Recruiting |
NCT00187434 -
Comparison of Two Methods of Continuous Positive Airway Pressure (CPAP) to Support Successful Extubation of Infants of Birth Weights ≤ 1500 Grams (C2CPAP)
|
N/A | |
| Completed |
NCT02687802 -
Respiratory Mechanics and Patient-ventilator Asynchrony Index in Patients With Invasive Mechanical Ventilation
|
||
| Not yet recruiting |
NCT05906030 -
Diaphragm Dysfunction and Ultrasound Perioperatively
|
||
| Completed |
NCT03850977 -
Is There an Association Between Chronic Pancreatitis and Pulmonary Function
|
||
| Completed |
NCT02845375 -
Effect of Neuromuscular Blockade and Reversal on Breathing
|
Phase 4 | |
| Recruiting |
NCT03309423 -
Is Venous to Arterial Conversion (v-TAC) of Blood Gas Reliable in Critical Ill Patients in the ICU?
|
N/A | |
| Completed |
NCT04115969 -
Outcome After Non-invasive Ventilation.
|
||
| Not yet recruiting |
NCT03687385 -
The Effect of High-flow Nasal Oxygenation to the Saturation During Analgo-sedation in Different ASA Risk Class Patients
|
N/A |