Respiratory Insufficiency Clinical Trial
Official title:
Changes in Spontaneous Ventilation in Response to Changes in Extracorporeal Carbon Dioxide Removal
In physiological conditions, spontaneous ventilation is controlled by blood carbon dioxide
(and pH) levels. In healthy animals, extracorporeal carbon dioxide removal leads to
hypoventilation or apnea (Kolobow et al., 1977). During acute respiratory insufficiency,
extracorporeal carbon dioxide removal may be used to control spontaneous ventilation,
limiting risks of lung damage and relieving dyspnea (Crotti et al., 2012). However, little
is known about how spontaneous ventilation changes in response to changes in extracorporeal
carbon dioxide removal during acute respiratory insufficiency, especially in humans.
Aim of this study is to monitor changes in spontaneous ventilation in awake patients treated
with extracorporeal gas exchange support because of acute respiratory insufficiency, in
response to changes in extracorporeal carbon dioxide removal.
n/a
Allocation: Non-Randomized, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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