Clinical Trials Logo
  1. Home
  2. Respiratory Diseases
  3. NCT00840723
  4. Details
NCT00840723 Clinical Trial

Bronchoscopy Assisted Sampling of Cells and Fluid From the Lower Respiratory Tract of Human Subjects

Respiratory Diseases Clinical Trial

— SCCOR Bronch  

Official title:
Bronchoscopy-Assisted Sampling of Cells and Fluid From the Lower Respiratory Tract of Human Subjects

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00840723
Other study ID # CTRC 2799
Secondary ID NHLBI P50-HL0849
Status Completed
Phase N/A
First received February 6, 2009
Last updated September 3, 2013
Start date February 2009
Est. completion date August 2013

Study information
Verified date September 2013
Source University of North Carolina, Chapel Hill
Contact n/a
Is FDA regulated No
Health authority United States: Federal GovernmentUnited States: Institutional Review Board
Study type Observational

Clinical Trial Summary

The purpose of this research study is to collect cells and liquid from the air passages of healthy adults, both smokers and non-smokers. These samples will be used for test-tube studies to explore mechanisms of diseases of the respiratory tract, and to compare the samples between people who smoke cigarettes and people who don't. Obtaining these samples requires an invasive procedure called "bronchoscopy".

Recruitment information / eligibility
Status Completed
Enrollment 30
Est. completion date August 2013
Est. primary completion date August 2013
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria:

- Current cigarette smokers

- Must be otherwise healthy with no chronic illness

Exclusion Criteria:

- Asthma

- Smoking related lung disease (including bronchitis)

Study Design

Observational Model: Case Control, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Locations
Country Name City State
United States UNC Center for Environmental Medicine, Asthma and Lung Biology Chapel Hill North Carolina

Sponsors (1)
Lead Sponsor Collaborator
University of North Carolina, Chapel Hill

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary The goal of this project is to define the effect of smoking on key aspects of airway biology. These studies will also provide crucial & novel definition of airway biology in smokers against which COPD & CF patients will be compared. At the time of bronchoscopy No
See also
  Status Clinical Trial Phase
Recruiting NCT04461821 - Exhaled Breath Analysis by Secondary Electrospray Ionization - Mass Spectrometry in Children and Adolescents
Recruiting NCT06267859 - Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children Early Phase 1
Completed NCT04386408 - Evaluation of the Effect of a Combination of Plant Extracts (BSL_EP027) on the Incidence of Respiratory Infections Phase 1
Recruiting NCT06229613 - Exhaled Breath Aerosol for the Etiological Diagnosis of Respiratory Tract Infections: a Pilot Study
Completed NCT02084043 - In Vitro Assessment of a Breath-synchronized Vibrating Mesh Nebulizer During Non Invasive Ventilation N/A
Completed NCT01113255 - Validation of a Simulated Clinical Evaluation of Ventilators Phase 2/Phase 3
Completed NCT00988000 - Initial Specialist Telephone Consultation With New Patients in Secondary Care N/A
Completed NCT02723890 - The Efficacy and Safety of Using the Novel Tyto Device N/A
Completed NCT00719784 - Vibration Response Imaging in the Diagnosis of Pulmonary Disease N/A
Completed NCT00823056 - The Effect of Probiotics on Infections in Toddlers Phase 3
Recruiting NCT06366113 - Time of Exercise Re-training With Chronic Obstructive Pulmonary Disease (COPD) N/A
Recruiting NCT05175313 - Transthoracic Ultrasonography Findings and Their Relation to Spirometric Indices in Patients With Obstructive and Restrictive Respiratory Diseases
Completed NCT02754947 - Need for the Assessment and Consultation Team (ACT) Following Anesthetic Care
Completed NCT01255592 - Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis Phase 2
Completed NCT05978011 - 2014TP001 - Assessing the Biology of the Injured Lung - Version 1
Recruiting NCT02717650 - The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis. N/A
Completed NCT01196533 - A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters N/A
Completed NCT02406053 - Oxidative Damage and Antioxidant Mechanisms in COPD N/A
Completed NCT01734629 - Pulmonary Disease in Patients Referred for Coronary CT N/A
Completed NCT00532896 - Impact of Weight Loss Following Bariatric Surgery on Pulmonary Function in Patients With Morbid Obesity N/A