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Respiratory Complication clinical trials

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NCT ID: NCT04263363 Active, not recruiting - Clinical trials for Obstructive Sleep Apnea

Applying Best Clinical Practices to Patients at High Risk of Respiratory Complications

Start date: February 18, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to: 1. Perform a retrospective analysis on data contained in the UCLA Perioperative Data Warehouse on the incidence of respiratory dysfunction in the post-operative care unit (PACU) before and after the introduction of sugammadex into clinical practice. 2. Develop and implement a clinical best practice pathway designed to prevent postoperative respiratory complications in higher risk patients (such as those with OSA or preexisting respiratory disease) using education and clinical decision support in patients.

NCT ID: NCT03967639 Active, not recruiting - Diabetes Mellitus Clinical Trials

Seasonal Trends of Respiratory Morbidity in Diabetic Patients

Start date: February 1, 2019
Phase:
Study type: Observational

Type 2 diabetes mellitus (T2DM) poses a significant burden on the patients and the health care system. The increasing number of surgery performed in elderly population results in an increased number of perioperative T2DM-related adverse effects. T2DM has a prevalence of 30-40% in a population undergoing cardiovascular surgery. Cardiac surgery, especially cardiopulmonary bypass (CPB) is also known to deteriorate respiratory mechanics. Therefore, the study is aimed at a retrospective analysis of seasonal trends in respiratory consequences of T2DM, i.e.: i: distribution of patients with and without T2DM presenting for elective cardiac surgery during the two-year examination period; ii: characterization of respiratory co-morbidities in the patients, iii: exploring whether the respiratory mechanics at presentation and those caused by cardiac surgery exhibit different trends in T2DM and control patients.

NCT ID: NCT03198208 Active, not recruiting - Surgery Clinical Trials

Intraoperative Fentanyl Dose on Respiratory Complications

Start date: January 1, 2007
Phase: N/A
Study type: Observational [Patient Registry]

Fentanyl is the most commonly used opioid during anesthesia at Massachusetts General Hospital. Compared to other opioids, e.g. sulfentanil and remifentanil, fentanyl's pharmacokinetic properties are more problematic as the context sensitive half-time increases with duration of fentanyl infusion. This may lead to respiratory complications particularly in patients who receive fentanyl for surgical procedures of long duration. Considering the common use of fentanyl during surgery and its duration of action that is hard to predict during long surgical procedures, we will evaluate the association between intraoperative fentanyl dose and postoperative respiratory complications within 3 days of surgery.