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Neuroinflammation in Hypertension Study — MINIHT  

Resistant Hypertension Clinical Trial

Official title:
The Role of Neuroinflammation in Hypertension.Minocycline for Resistant Hypertension: a Randomized Double Blind Placebo-Controlled Trial

Clinical Trial Summary

To demonstrate that in patients with resistant hypertension oral treatment with minocycline via inhibition of central immune cell activation and inflammation results in reduced central sympathetic outflow and concomitant lowering of BP.

Clinical Trial Description

This is a randomized, double-blind, placebo controlled, parallel group design study aiming to compare the effects of minocycline 100mg twice daily vs matched placebo for 12 weeks on ambulatory BP and the parameters of sympathetic and immune activation ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04478500
Study type Interventional
Source Royal Perth Hospital
Contact Revathy Carnagarin, MD
Phone +61892240316
Email revathy.carnagarin@uwa.edu.au
Status Recruiting
Phase Phase 3
Start date July 2, 2020
Completion date February 1, 2025
View Details
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