Variable Resistance Training in Patients With Osteoarthrosis of the Knee

Resistance Training Clinical Trial

Official title:

Variable Resistance Training Versus Conventional Rubber Band Training: Effects on Functional Capacity and Strength in Patients With Osteoarthrosis of the Knee

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03722277
• Other study ID #: Variable Load
• Status: Not yet recruiting
• Phase: N/A
• Start date: October 22, 2018
• Est. completion date: September 1, 2020

Study information

• Verified date: October 2018
• Source: University College South Denmark
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This is a randomized controlled trial investigating the effect of variable load training in patients with knee osteoarthrosis.

The intervention will consist of resistance training with variable load in knee extension- and flexion. The control group will receive conventional strength training with rubber band.

Outcome measures will be the Knee Osteoarthrosis Outcome Score, functional capacity measured in a sit to stand test, 30m. pace walk and a 9 step stair climb test. Additionally isometric strength in knee flexion- and extension will be measured.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 36
• Est. completion date: September 1, 2020
• Est. primary completion date: December 31, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 50 Years and older

Eligibility

Inclusion Criteria:

• Knee pain and minimum three of the following

• >50 years

• morning stiffness < 30 min

• crepitation

• bone tenderness

• bone osteophytes

• absence of inflammation

Exclusion Criteria:

• Other causes of symptoms to the knee

Related Conditions & MeSH terms

• Osteoarthritis
• Resistance Training

Intervention

Other:
• Variable load training
Based on symptoms/strength measured in an isometric maximum strength test at five different angles of knee flexion- and extension, participants will be training with variable load during both concentric and excentric phase of the dynamic movement. Initially participants will start at 40% of symptom limited isometric strength, this will increase to 50% during the training period.
• Conventional strength training
Conventional strength training with rubber bands in knee flexion- and extension, additionally hip abduction- and adduction.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University College South Denmark

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in self reported knee function	Knee Osteoarthrosis Outcome Score (100-0, 100 indicating no symptoms and 0 indicating extreme symptoms)	At baseline and 10 weeks follow up
Secondary	Change in functional capacity	Sit to stand test	At baseline and 10 weeks follow up
Secondary	Change in isometric strength	Isometric strength in knee flexion- and extension	At baseline and 10 weeks follow up
Secondary	Change in functional capacity	30m pace walk	At baseline and 10 weeks follow up
Secondary	Change in functional capacity	9 step stair climb test	At baseline and 10 weeks follow up