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Observational Study in Bariatric Surgery — NEOCURE  

Obesity Clinical Trial

Official title:
Observational Study of the Pharmacological Reversal of the Residual Neuromuscular Blockade in Bariatric Surgery

Clinical Trial Summary

Obesity in the world represents a growing share of the general population. At hospital, the management of these patients could be problematic especially when calculating the drug dosage. According to the French guidelines, neostigmine, a cholinesterase inhibitor, should be used to reverse a residual neuromuscular blockade at a dose of 0.4 mg/kg of total body weight in non-obese patients. In morbidly-obese patients, with the modification of the fat/lean mass ratio, the optimal dose of neostigmine is non-consensual. To calculate the dose of neostigmine, some anesthesiologists use the total body weight, others use the ideal body weight and others use the adjusted body weight. Due to this practice variability, It may be useful to observe the mean time to recovery of neuromuscular blockade and side effects after pharmacological reversal according to the dosage of neostigmine.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04244266
Study type Observational
Source Poitiers University Hospital
Contact
Status Completed
Phase
Start date January 29, 2020
Completion date June 14, 2023
View Details
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