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NCT04316468 Clinical Trial

Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation

Reperfusion Injury Clinical Trial

Official title:
Evaluation of Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation

Clinical Trial Details — Status: Terminated

Administrative data
NCT number NCT04316468
Other study ID # 20-001209
Secondary ID
Status Terminated
Phase
First received
Last updated
Start date March 10, 2020
Est. completion date April 8, 2024

Study information
Verified date April 2024
Source Mayo Clinic
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Researchers are trying to improve the understanding of systolic function of the heart at the time of liver reperfusion in patients undergoing orthotopic liver transplantation.

Recruitment information / eligibility
Status Terminated
Enrollment 20
Est. completion date April 8, 2024
Est. primary completion date April 8, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Age greater than 18 years - Undergoing primary orthotopic liver transplantation Exclusion Criteria: - Redo orthotopic transplantation - Acute or fulminant liver failure - Patient with pre-existing atrial fibrillation or hypertrophic cardiomyopathy - Patients with an abnormal preoperative stress test (EF <55%, areas of prior infarct, ongoing ischemia)

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States Mayo Clinic in Florida Jacksonville Florida

Sponsors (1)
Lead Sponsor Collaborator
Mayo Clinic

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Degree of change in cardiac strain Evaluate the degree of change to cardiac strain using speckle tracking echocardiography Up to 1 hour after graft reperfusion
Secondary Pattern of right and left ventricular strain Describe the pattern of right and left ventricular strain throughout the course of orthotopic liver transplantion. Up to 5 hours from the time of surgery start
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