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Clinical Trial Summary

In the treatment of heart failure (HF), SGLT-2 inhibitor (SGLT-2i) can significantly improve the clinical outcome and quality of life related to HF. The current data show that SGLT-2i is effective and safe in improving HF outcomes in patients with chronic kidney disease (CKD) stage 4, but there is little clinical evidence in patients with eGFR<20 ml/min/1.73 m2. Therefore, our research is designed to confirm that SGLT-2i can improve the outcome of HF in patients with chronic heart failure with reduced ejection fraction (HFrEF) and severe chronic renal insufficiency (eGFR<20ml/min/1.73m2).


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05737186
Study type Interventional
Source Peking University People's Hospital
Contact
Status Terminated
Phase Phase 4
Start date March 9, 2023
Completion date April 16, 2024

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