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Renal Impairment clinical trials

View clinical trials related to Renal Impairment.

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NCT ID: NCT05927415 Active, not recruiting - Renal Impairment Clinical Trials

A Study to Test How Kidney Problems Influence the Blood Concentrations of Efgartigimod

Start date: July 17, 2023
Phase: Phase 1
Study type: Interventional

A study to test how kidney problems influence the blood concentrations of efgartigimod

NCT ID: NCT05916573 Completed - Renal Impairment Clinical Trials

A Study to Evaluate the Pharmacokinetics of HSK16149 in Subjects With Renal Impairment

Start date: December 12, 2022
Phase: Phase 1
Study type: Interventional

This is an open-label, single-dose study to evaluate the pharmacokinetics and safety of HSK16149 in subjects with mild, moderate and severe renal impairment compared to the matched control subjects with normal renal function.

NCT ID: NCT05878704 Recruiting - Renal Impairment Clinical Trials

Study of GBT021601 in Participants With Renal Impairment

Start date: June 29, 2023
Phase: Phase 1
Study type: Interventional

Renal Impairment study of GBT021601.

NCT ID: NCT05865171 Recruiting - Renal Impairment Clinical Trials

A Study to Evaluate Pharmacokinetics (PK) and Safety of Inaxaplin in Participants With Renal Impairment

Start date: June 12, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the pharmacokinetics and safety of a single dose of Inaxaplin (IXP) in participants with severe renal impairment and healthy participants with normal renal function.

NCT ID: NCT05844228 Recruiting - Renal Impairment Clinical Trials

A Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics and Safety of VIR-2218

Start date: June 1, 2023
Phase: Phase 1
Study type: Interventional

The rationale of this study is to evaluate the impact of renal function on the PK, safety, and tolerability of VIR-2218 in participants with normal renal function and participants with varying degrees of renal dysfunction who are otherwise medically stable

NCT ID: NCT05812417 Recruiting - Healthy Clinical Trials

A Study to Evaluate the Effects of Renal Function on Pharmacokinetics and Safety of DA-8010

Start date: April 10, 2023
Phase: Phase 1
Study type: Interventional

This Study will evaluate the effects of renal function on pharmacokinetics and safety of DA-8010

NCT ID: NCT05793450 Completed - Renal Impairment Clinical Trials

Pharmacokinetics of IBI362 in Subjects With and Without Renal Impairment

Start date: May 5, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess how fast IBI362 gets into the blood stream and how long it takes the body to remove it in participants with impaired kidney function compared to healthy participants.

NCT ID: NCT05731804 Not yet recruiting - Hepatic Impairment Clinical Trials

Hepatic Impairment and Renal Impairment Study of SIM0417 Combined With Ritonavir

Start date: March 1, 2023
Phase: Phase 1
Study type: Interventional

This is a multicenter, nonrandomized, open-label, parallel controlled Phase I clinical study to evaluate the Pharmacokinetics, Safety and Tolerability of SIM0417 combined with ritonavir after a single dose in subjects with mild and moderate renal impairment, moderate hepatic impairment, normal renal function, and normal hepatic function. It is divided into Part A (subjects with mild/moderate renal impairment and subjects with normal renal function) and Part B (subjects with moderate hepatic impairment and subjects with normal hepatic function).

NCT ID: NCT05711381 Completed - Renal Impairment Clinical Trials

Phase 1 PK Study to Assess Safety, PK, Tolerability of HM15912 in Subjects With Renal Impairment and Normal Renal Function

Start date: December 2, 2022
Phase: Phase 1
Study type: Interventional

An Open-label, Single-dose Study to Evaluate the Pharmacokinetics, Safety and Tolerability of HM15912 in Subjects with Renal Impairment and Matched Control Subjects with Normal Renal Function

NCT ID: NCT05673603 Completed - Renal Impairment Clinical Trials

A Study of Brensocatib Following a Single Oral Administration in Participants With or Without Renal Impairment

Start date: July 20, 2021
Phase: Phase 1
Study type: Interventional

The primary purpose of the study is to determine the pharmacokinetics (PK) following a single oral dose administration of brensocatib, safety, and tolerability of brensocatib when administered to participants with impaired renal function and in healthy participants.