Cohort Follow-up: Progression and Consequences of Chronic Kidney Disease.

Renal Function Disorder Clinical Trial

— NéphroTest  

Official title:

Cohort Follow-up: Progression and Consequences of Chronic Kidney Disease.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04070885
• Other study ID #: CHUBX 2009/29
• Status: Completed
• Start date: January 5, 2011
• Est. completion date: March 20, 2015

Study information

• Verified date: August 2019
• Source: University Hospital, Bordeaux
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study aims to conduct a prospective collection of clinical and para-clinical data in patients with Chronic Renal Diseases to identify disease progression factors, markers of renal function, and the pathophysiology of Chronic Renal Diseases complications.

Description:

Chronic Renal Diseases have a growing incidence and prevalence in France, with significant consequences in terms of morbidity and mortality, especially cardiovascular, and Public Health.

It is necessary to know better:

• the mechanisms leading to the progression of the Chronic Renal Diseases

• markers to quantify renal function and progression of the Chronic Renal Diseases

• the pathophysiology of Chronic Renal Diseases complications, cardiovascular, nutritional, or mineral metabolism in particular.

This study aims to conduct a prospective collection of clinical and para-clinical data in patients with Chronic Renal Diseases to identify disease progression factors, markers of renal function, and the pathophysiology of Chronic Renal Diseases complications.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 210
• Est. completion date: March 20, 2015
• Est. primary completion date: March 20, 2015
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients with Chronic Renal Disease, stage 2 to 5, non-dialysis patients over the age of 18,

• followed in the Nephrology Department of the Bordeaux University Hospital

• agreeing to participate in NephroTest

• affiliated with social security.

Exclusion Criteria:

• Patients under 18 years

• Patients with acute or rapidly progressive renal failure

• Patients with severe comorbidities or comorbidities that are life-threatening in the short term (<1 year)

• Patients who did not give their written consent to be included in the study

• Major incapacitated patients and psychiatric patients admitted to hospital

Related Conditions & MeSH terms

• Chronic Renal Diseases
• Kidney Diseases
• Kidney Failure, Chronic
• Renal Function Disorder
• Renal Insufficiency, Chronic

Intervention

Procedure:
• Blood sample
A dry tube of 7 ml of blood, two 4 ml EDTA tubes, a 4 ml heparinized tube and an 8.5 ml ACD-A tube will be collected from the patient.
• Urine sample
The urine will be taken from three 15 ml tubes.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Bordeaux

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Estimated Glomerular Filtration Rate measurement	by isotope technique	At 1 year after inclusion
Primary	Estimated Glomerular Filtration Rate measurement	by isotope technique	At 2 year after inclusion
Primary	Measured Glomerular Filtration Rate	by isotope technique	At 1 year after inclusion
Primary	Measured Glomerular Filtration Rate	by isotope technique	At 2 years after inclusion