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Renal Failure, End-stage clinical trials

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NCT ID: NCT02331030 Completed - Clinical trials for Kidney Failure, Chronic

A Randomised Trial Comparing Supraclavicular Block vs Supraclavicular and Pecs II Block in Arteriovenous Grafting

Start date: December 2014
Phase: N/A
Study type: Interventional

This study evaluates the addition of Pecs II block to ultrasound-guided supraclavicular brachial plexus block in patients undergoing arteriovenous graft creation surgery. Participants will be randomised into two equal groups, one receiving supraclavicular and pecs II blocks, the other receiving supraclavicular block and sham block (Grade 1).

NCT ID: NCT02297451 Completed - Clinical trials for Renal Failure, End-Stage

Trial Comparing the Incidence of Steal Syndrome in the Two Types of anTEcubitaL Fossa Arteriovenous fistuLa AVF

STEAL
Start date: February 2011
Phase: N/A
Study type: Interventional

Background: Arteriovenous fistula (AVF) is a form of vascular access for haemodialysis. An AVF is normally created at the level of the wrist, but occasionally it is created in the elbow when there is no suitable vessel in the forearm. The most common type of elbow (antecubital) fistula (AFF) is a brachiocephalic fistula, which carries significantly higher risk of steal syndrome (AVF-associated hand ischaemia) than wrist fistulas. More recently, AFF using proximal radial or ulnar artery as inflow has been described and shown to have a lower rate of Steal syndrome than brachiocephalic fistula. This study aims to investigate the incidence of steal syndrome between AFF using brachial artery and that using the proximal radial/ulnar artery as inflow.

NCT ID: NCT02252055 Completed - Clinical trials for Renal Failure, End Stage

The ONE Study ATDC Trial

ONEatDC
Start date: March 19, 2015
Phase: Phase 1/Phase 2
Study type: Interventional

To collect evidence of the safety of administering autologous tolerogenic dendritic cells (ATDC) preparations to living-donor renal transplant recipients in the context of an international European Union funded consortium aimed at evaluationg cellular immunotherapy in solid organ transplantation (The ONE Study). It is anticipated that immune regulation induced by ATDC therapy can evntually be used to reduce the need for conventional immunosuppression in transplant recipients.

NCT ID: NCT02139917 Completed - Palliative Care Clinical Trials

Effects of a Transitional Palliative Care Model on Patients With End-stage Renal Failure

ESRF
Start date: August 2014
Phase: N/A
Study type: Interventional

Primary aim: 1. To compare the effects of customary care and an interventional Home-based Palliative Renal Program (HBPRP) for ESRF patients 2. To compare the effects of customary care and Home-based Palliative Program (HBPP) for ESRF patients Secondary aim: 3. To explore the lived experiences of patients with ESRF. Hypothesis The transitional renal palliative care model is associated with decreased in unscheduled hospital readmission, reduce length of stay as well as improved quality of life for patients with end-stage renal failure.

NCT ID: NCT02085629 Terminated - Clinical trials for Renal Failure, End Stage

The ONE Study M Reg Trial

ONEmreg12
Start date: July 24, 2014
Phase: Phase 1/Phase 2
Study type: Interventional

To collect evidence of the safety of administering donor-derived regulatory macrophage (M reg) preparations to living-donor renal transplant recipients in the context of an international European Union funded consortium aimed at evaluating cellular immunotherapy in solid organ transplantation (The ONE Study). It is anticipated that immune regulation induced by M reg therapy can eventually be used to reduce the need for conventional immunosuppression in transplant recipients.

NCT ID: NCT01691196 Withdrawn - Obesity Clinical Trials

Inflammation in Peritoneal Dialysis Patients: Effect of Obesity

Start date: September 2012
Phase:
Study type: Observational

Our study addresses the following research question: What is the role of obesity in modulating inflammation and innate immune function, as well as the overall responsiveness of innate immune cells (such as macrophages, neutrophils, and other peripheral leukocytes) in patients undergoing peritoneal dialysis? The investigators hypothesize that obesity will lead to increased inflammation in patients undergoing peritoneal dialysis.

NCT ID: NCT00291863 Recruiting - Peritoneal Dialysis Clinical Trials

Simvastatin Effect on End Stage Renal Failure Patients Treated by Peritoneal Dialysis

Start date: February 2006
Phase: Phase 4
Study type: Interventional

This study will analyse the effect of simvastatin on endothelium dependent venodilation in chronic renal failure patients treated by peritoneal dialysis. The hypothesis is that patients will have a greater endothelium dependent venodilation after four months of simvastatin use.