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Comparison Between HA330 Hemoperfusion Filter Hemodialysis and Conventional High-Flux Hemodialysis Filter

Sepsis Clinical Trial

Official title:
Comparison Between HA330 Hemoperfusion Filter Hemodialysis and Conventional High-Flux Filter Hemodialysis in Reducing Inflammatory Mediators in Renal Dysfunction Due to Sepsis

Clinical Trial Summary

The purpose of this study is to compare the effectiveness between conventional hemodialysis and hemodialysis using hemoperfusion adsorbents in renal dysfunction caused by sepsis

Clinical Trial Description

This study is an open randomized clinical trial. Data were taken prospectively until the number of samples was fulfilled for analysis. Due to the intervention provided, this study was not blinded. Subjects were divided into 2 groups (group undergoing conventional hemodialysis and group undergoing HA330 hemoperfusion). Both groups underwent therapy for 4 hours, 3 times a week, with two days apart between dialysis. Inflammatory mediator levels were assessed 4 times, before and after each intervention. All subjects were given standard therapy as indicated such as antibiotics, oxygen supplementation, administration of vasopressors, nutrition, and other therapies as indicated. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05941624
Study type Interventional
Source Indonesia University
Contact Dita Aditianingsih, M.D.
Phone +628151819244
Email ditaaditiaa@gmail.com
Status Recruiting
Phase N/A
Start date June 16, 2023
Completion date March 31, 2024
View Details
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