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Renal Dialysis clinical trials

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NCT ID: NCT01125202 Completed - Renal Dialysis Clinical Trials

Intervention to Reduce Dietary Sodium in Hemodialysis

BalanceWise-HD
Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to test, in a randomized clinical trial of 200 hemodialysis patients, a behavioral intervention to reduce dietary sodium intake. The investigators will assess the impact on weight gain between dialysis treatments, blood pressures, symptoms, and health-related quality of life. The primary study hypotheses are that participants will gain less weight in between dialysis treatments, and that dietary recalls will demonstrate reduced consumption of dietary sodium.

NCT ID: NCT01092455 Completed - Renal Dialysis Clinical Trials

Multi-center Study to Investigate the Effects of Citrasate® on Heparin N Requirements During Hemodialysis Treatment

Start date: December 2009
Phase: Phase 4
Study type: Observational

The purpose of this study is to determine whether the use of Citrasate®, citric acid dialysate enables the reduction of the heparin N (anticoagulant) dose in patients undergoing hemodialysis.

NCT ID: NCT01057407 Completed - Clinical trials for Chronic Kidney Disease

A Comparative Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia on Hemodialysis

Start date: January 2010
Phase: Phase 3
Study type: Interventional

This is a multi-center, open-labeled study to examine the non-inferiority of ASP1585 to sevelamer hydrochloride in chronic kidney disease patients with hyperphosphatemia on hemodialysis.

NCT ID: NCT01021839 Completed - Kidney Failure Clinical Trials

Comparison of Bovine Carotid Artery and Expanded Polytetrafluoroethylene (ePTFE) for Permanent Hemodialysis Access

Start date: April 2006
Phase: N/A
Study type: Interventional

The investigators did a randomized control trial comparing bovine carotid artery grafts with ePTFE grafts for patients that need hemodialysis access. The goal of the study was to determine differences in primary and assisted patency rates and frequency of complications between these two types of grafts. The investigators' hypothesis was that bovine carotid artery grafts more closely mimic autologous tissue and therefore, would provide better patency and fewer complications.

NCT ID: NCT01017276 Completed - Clinical trials for Chronic Kidney Disease

A Phase 3 Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Peritoneal Dialysis

Start date: November 2009
Phase: Phase 3
Study type: Interventional

This is a multi-center, open-labeled, non-comparative study to examine the safety and efficacy of ASP1585 in chronic kidney disease and hyperphosphatemia patients on peritoneal dialysis.

NCT ID: NCT00943995 Completed - Clinical trials for Kidney Failure, Chronic

Three Times Weekly (TIW) Growth Hormone Therapy in Children on Hemodialysis

Start date: July 2010
Phase: Phase 3
Study type: Interventional

Hypotheses: 1. The provision of thrice weekly subcutaneous (SQ) recombinant growth hormone (rGH) therapy to children receiving in-center hemodialysis (HD) will result in improved growth. 2. The provision of thrice weekly SQ rGH therapy to children receiving in-center HD will result in improved lean body mass, nutritional status and quality of life. TIW rGH treatment regimen (0.35 mg/kg/week divided into 3 doses, each dose being given at the conclusion of the dialysis treatment) for up to 2 years; growth response, Dual energy X-ray absorptiometry (DEXA), and quality of life (QOL) will be measured. The goal is to enroll 20 children who are Tanner 1 with decreased height SDS and/or decreased height velocity standard deviation scoreS (SDS). If this therapy is demonstrated to be efficacious and improves growth and QOL, this therapy could be easily implemented for all eligible children on HD, since parental acceptance should be better without having to administer the rGH at home and compliance for the child will be assured. The investigators thus propose an important study that has the ability to advance their understanding and provide evidence for the best methods to promote growth in children on dialysis. The results of this study will result in important information that will be of value to the entire pediatric nephrologist community, including health care professionals, patients, and families. In a real sense, this study will build on the 2006 Consensus Conference guidelines for evaluation and treatment of growth failure in children with chronic kidney disease (CKD). This will provide evidence for critical management decisions that can help insure better growth opportunities to more children with CKD.

NCT ID: NCT00921089 Completed - Clinical trials for Cardiovascular Diseases

Vascular Calcification, Inflammation and Coronary Flow Velocity in Hemodialysis Patients

Start date: April 2008
Phase: N/A
Study type: Observational

The aim of this cross-sectional study is to determine the correlation of coronary artery calcification as measured by electron-beam computerized tomography and coronary flow reserve measured by trans-thoracic Doppler echocardiography in hemodialysis patients. The investigators also assessed the carotid artery parameters by measuring intima media thickness that can accurately describe the process of arterial wall changes due to atherosclerosis. Possible association of coronary flow reserve with inflammation and arterial calcification in hemodialysis patients was also evaluated.

NCT ID: NCT00892749 Completed - Clinical trials for Chronic Kidney Disease

Long-term Study in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis

Start date: May 2009
Phase: Phase 3
Study type: Interventional

This is a multi-center, open-labeled, non-comparative study to examine the safety and efficacy of ASP1585 for long-term dosing in chronic kidney disease and hyperphosphatemia patients on hemodialysis.

NCT ID: NCT00824837 Completed - Renal Dialysis Clinical Trials

Study of beta2-Microglobulin Removal by Standard Versus New High Cut-Off Haemodialysis Membrane

HiCOF
Start date: October 2008
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine whether a novel haemodialysis membrane, compared with the standard dialysis membrane, will increase the removal of beta2-microglobulin in chronic dialysis patients.

NCT ID: NCT00806130 Completed - Clinical trials for Chronic Kidney Failure

Health Related Quality of Life and Cognitive Function Among Norwegian Dialysis Patients

Start date: September 2008
Phase:
Study type: Observational

The purpose of this study is to assess health related quality of life and its predictors among chronic dialysis patients and to assess cognitive function using 3 different tests. (undergraduate medical student research project; not published)