Intranasal Desmopressin vs IV Ketorolac in Renal Colic Pain Control

Renal Colic Clinical Trial

Official title:

Comparison of Intranasal Desmopressin vs IV Ketorolac in Renal Colic Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02937896
• Other study ID #: 688
• Status: Completed
• Phase: N/A
• First received: October 12, 2016
• Last updated: October 18, 2016
• Start date: January 2015
• Est. completion date: April 2016

Study information

• Verified date: October 2016
• Source: Shahid Beheshti University of Medical Sciences
• Contact: n/a
• Is FDA regulated: No
• Health authority: Iran: Ministry of Health
• Study type: Interventional

Clinical Trial Summary

The aim of this study is the comparison of efficacy of intravenous ketorolac and intranasal desmopressin in renal colic patients pain control.

Description:

40 renal colic patients have been divided into 2 groups randomly, one group has been received 30mg intravenous Ketorolac and 4 puffs nasal Normal Saline while other has been received 40 micrograms nasal Desmopressin and 1cc intravenous Normal Saline. Pain Score before drug administration,also 10, 30 and 60 minutes after drug administration has been measured bye Visual Analogue Scale ( VAS ).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: April 2016
• Est. primary completion date: February 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 16 Years to 50 Years

Eligibility

Inclusion Criteria:

• renal colic patients

Exclusion Criteria:

• history of hypertension and cardiac disease

• pregnant patients

• use of analgesic within 4 hours before intervention

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Colic
• Renal Colic

Intervention

Drug:
• Desmopressin
40 micrograms Nasal Desmopressin.
• Ketorolac
30mg intravenous Ketorolac.
• Normal Saline
1cc intravenous Normal Saline.
• Normal Saline
4 puffs nasal Normal Saline.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Shahid Beheshti University of Medical Sciences

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain score		Pain score change from baseline pain score before intervention 10, 30 and 60 minutes after intervention	Yes